|1.||Elisabetsky, Elaine: 4 articles (12/2012 - 08/2004)|
|2.||Okunji, Christopher O: 3 articles (12/2012 - 08/2008)|
|3.||Linck, Viviane M: 2 articles (12/2012 - 01/2011)|
|4.||Herrmann, Ana P: 2 articles (12/2012 - 01/2011)|
|5.||Elisabetsky, E: 2 articles (01/2012 - 03/2006)|
|6.||Iwu, Maurice M: 2 articles (01/2011 - 08/2008)|
|7.||Younai, Ashkaan: 1 article (06/2015)|
|8.||Zeng, Bi-Shun: 1 article (06/2015)|
|9.||Scheidt, Karl A: 1 article (06/2015)|
|10.||Meltzer, Herbert Y: 1 article (06/2015)|
|1.||Schizophrenia (Dementia Praecox)
01/10/2012 - "This study presents additional evidence that 5-HT2A/C receptors are central to the antipsychotic-like effects of alstonine, consistently seen in mouse models relevant to the three dimensions of schizophrenia symptoms."
08/01/2008 - "This study reinforces and complements the antipsychotic-like profile of alstonine, and emphasizes its potential as a drug useful for the management of negative symptoms in schizophrenia."
12/01/2012 - "This study shows that alstonine decreases glutamate uptake, which may be beneficial to the glutamatergic deficit observed in schizophrenia. "
08/01/2008 - "Moreover, MK801-induced social withdrawal was completely prevented by sulpiride (10 mg/kg) and alstonine 1.0 mg/kg, and partially prevented by alstonine 0.5 mg/kg. The study indicates that alstonine not only increases social interaction in normal mice, but also averts social deficits attributable to negative symptoms of schizophrenia. "
12/01/2012 - "An additional potential benefit of alstonine as an antipsychotic is its ability to increase glutathione, a key cellular antioxidant reported to be decreased in the brain of patients with schizophrenia. "
11/01/2006 - "A bioactive beta-carboline alkaloid, alstonine, present in this extract was previously shown to have anti-cancer activity against cancer cell lines. "
01/01/1982 - "Among them, alstonine, serpentine, sempervirine and flavopereirine, all alkaloids which belong to the Beta-carboline class, distinguish cancer DNA from healthy tissue DNA inhibit DNA in vitro synthesis when native DNA from different cancerous tissues or cells is used as template. "
01/01/1999 - "Atypical features of alstonine were the prevention of haloperidol-induced catalepsy and lack of direct interaction with D1, D2 and 5-HT2A receptors, classically linked to antipsychotic mechanism of action."
05/01/1998 - "Atypical features of alstonine were the prevention of haloperidol-induced catalepsy and lack of direct interaction with D1, D2 and 5-HT2A receptors, classically linked to antipsychotic mechanism of action."
|4.||Nervous System Diseases (Neurological Disorders)
|1.||Glutamic Acid (Glutamate)
|5.||Dizocilpine Maleate (Dizocilpine)
|6.||Antipsychotic Agents (Antipsychotics)
|7.||Serotonin (5 Hydroxytryptamine)
|9.||Glutathione (Reduced Glutathione)