|1.||Chen, Tianfeng: 6 articles (05/2014 - 11/2008)|
|2.||Wong, Yum-Shing: 6 articles (05/2014 - 11/2008)|
|3.||Tsantili-Kakoulidou, Anna: 3 articles (02/2011 - 01/2005)|
|4.||Li, Xiaoling: 2 articles (05/2014 - 01/2013)|
|5.||Fan, Cundong: 2 articles (05/2014 - 12/2013)|
|6.||Zheng, Wenjie: 2 articles (05/2014 - 12/2013)|
|7.||Chen, T: 2 articles (01/2014 - 09/2008)|
|8.||Ochsenkühn-Petropoulou, Maria: 2 articles (02/2011 - 08/2007)|
|9.||Tsopelas, Fotios: 2 articles (02/2011 - 08/2007)|
|10.||Qiu, Wanshou: 1 article (11/2015)|
02/01/2009 - "Our results suggest a possible role of ROS as a mediator of the signaling pathway of selenocystine-induced, DNA damage-mediated apoptosis in susceptible cancer cells."
02/01/2009 - "A panel of eight human cancer cell lines was shown to be susceptible to selenocystine, with IC(50) values ranging from 3.6 to 37.0 microM. "
11/26/2008 - "Selenocystine (SeC) is a nutritionally available selenoamino acid with selective anticancer effects on a number of human cancer cell lines. "
01/01/2005 - "After an additional 16 weeks on the diets, two compounds, OSCA and selenocystine, significantly reduced lung adenoma multiplicity from 7.2 tumors per mouse in the NNK group to 4.5 and 4.6 tumors per mouse, respectively. "
02/01/2009 - "Mechanistic studies showed time- and dose-dependent increases in intracellular reactive oxygen species (ROS) in susceptible cancer cells (MCF7 and HepG2 cells) treated with selenocystine. "
03/01/2009 - "In the present study, we showed that selenocystine (SeC), a naturally occurring selenoamino acid, induced caspase-independent apoptosis in MCF-7 breast carcinoma cells, which was accompanied by poly(ADP-ribose) polymerase (PARP) cleavage, caspase activation, DNA fragmentation, phosphatidylserine exposure and nuclear condensation. "
03/01/2009 - "Selenocystine induces caspase-independent apoptosis in MCF-7 human breast carcinoma cells with involvement of p53 phosphorylation and reactive oxygen species generation."
12/01/2001 - "The transport and uptake of the most common Se compounds, selenate (SeO42-), selenite (SeO3(2-)), selenomethionine, and selenocystine, were investigated using confluent monolayers of Caco-2 cells, a human carcinoma cell line. "
05/01/2011 - "In this study, selenocystine, a nutritionally available selenoamino acid, was identified for the first time as a novel agent with anti proliferative activity on human keloids. "
05/01/2011 - "The range of the down-regulated genes and the degree of the decreased expression appeared to be correlated with the degree of the morphological alterations in selenocystine treated keloids."
05/01/2011 - "Prominent down-regulation of genes involved in development, cell adhesion and cytoskeleton, as well as extra cellular matrix genes, usually strongly up-regulated in keloids, resulted following selenocystine exposure. "
05/01/2011 - "We analyzed the gene expression profile of selenocystine treatment response in keloid fibroblasts by the microarray system to characterize the effects of selenocystine on human keloids. "
05/01/2011 - "Effect of selenocystine on gene expression profiles in human keloid fibroblasts."
|4.||Hepatocellular Carcinoma (Hepatoma)
05/15/2014 - "Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling."
01/01/2013 - "Natural borneol, a monoterpenoid compound, potentiates selenocystine-induced apoptosis in human hepatocellular carcinoma cells by enhancement of cellular uptake and activation of ROS-mediated DNA damage."
12/15/2003 - "The toxicities of six different selenium compounds (selenite, selenate, selenocystine, selenocystamine, selenodioxide, and selenomethionine) have now been compared in HepG2 human hepatoma cells and isolated rat liver mitochondria. "
08/15/2007 - "The retention behaviour of selenites (Se(IV)), selenates (Se(VI)), seleno-dl-methionine (Se-Met), selenocystine (Se-Cyst), selenocystamine (Se-CM) and selenourea (Se-U) was investigated using a Discovery end-capped reversed-phase column as stationary phase and different mobile phase conditions. "
01/01/2005 - "In this work the lipophilicity of different selenium species occurring in environmental matrices and food, Se(IV), Se(VI), selenomethionine (Se-Met), selenocystamine (Se-CM), selenocystine (Se-Cyst), and dimethyl diselenide (CH3)2Se2, was investigated in the octanol-water system, using the shaking flask method and detection with inductively coupled plasma-atomic emission spectrometry (ICP-AES), in order to assess their environmental fate and tendency to bioaccumulate. "
02/01/2011 - "In the present work, the chromatographic behavior of eight selenium species, namely selenites (Se(IV)), selenates (Se(VI)), seleno-DL-methionine (Se-Met), selenocystine (Se-Cyst), selenocystamine (Se-CM), selenourea (Se-U), dimethylselenide ((CH(3))(2) Se) and dimethyldiselenide ((CH(3))(2) Se(2)), was investigated under different stationary and mobile phase conditions, in an effort to unravel secondary interferences in their underlying elution mechanism. "
|1.||Reactive Oxygen Species (Oxygen Radicals)
|2.||Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
|3.||Sodium Selenite (Selenite)
|6.||selenic acid (selenate)
|10.||Glutathione (Reduced Glutathione)