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reumycin
isolated from Actinomyces; structure
Also Known As:
6-methylpyrimido(5,4-e)-as-triazine-5,7(6H,8H)- dione; N-1-demethylxanthotricin; rheumycin
Networked:
4
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Triazines: 306
reumycin: 4
Related Diseases
1.
Neoplasms (Cancer)
03/01/1991 - "
Among the reumycin resistant tumors, the cultures of one of the glioblastomas showed stimulation of proliferation, which justifies the necessity for testing the individual sensitivity of the tumor to reumycin in each concrete patient.
"
03/01/1991 - "
In tissue cultures 71.5% of gliomas were sensitive to reumycin, in the subcapsular test 75% of tumors proved to be reumycin sensitive with fluctuations of inhibited growth of heterotransplants within a range of 27-75%.
"
08/01/1985 - "
The pharmacokinetics of reumycin, an antitumor antibiotic, was studied with high performance liquid chromatography in patients with tumors of the brain and kidneys.
"
04/01/1983 - "
A possibility of enhance the reumycin potency may involve the pH lowering inside the tumor cells - for example, by glucose injections.
"
03/01/1987 - "
The antineoplastic reumycin, proxyphein, and prospidin cause no toxic reactions of the brain and meninges on injection by the above mentioned methods; they are recommended for approbation in the neurooncological clinic for the treatment of patients with malignant tumors of the brain by injection into the system of the cerebrospinal fluid.
"
2.
Glioma (Gliomas)
03/01/1991 - "
In tissue cultures 71.5% of gliomas were sensitive to reumycin, in the subcapsular test 75% of tumors proved to be reumycin sensitive with fluctuations of inhibited growth of heterotransplants within a range of 27-75%.
"
3.
Glioblastoma (Glioblastoma Multiforme)
03/01/1991 - "
Among the reumycin resistant tumors, the cultures of one of the glioblastomas showed stimulation of proliferation, which justifies the necessity for testing the individual sensitivity of the tumor to reumycin in each concrete patient.
"
Related Drugs and Biologics
1.
Antineoplastic Agents (Antineoplastics)
2.
Anti-Bacterial Agents (Antibiotics)
3.
Capsules (Microcapsules)
4.
Prospidium (Prospidium Chloride)
5.
Glucose (Dextrose)
Related Therapies and Procedures
1.
Injections