|1.||Marquez, Victor E: 10 articles (02/2012 - 03/2003)|
|2.||Jones, Peter A: 6 articles (09/2008 - 03/2003)|
|3.||Cheng, Jonathan C: 5 articles (11/2005 - 03/2003)|
|4.||Yoo, Christine B: 4 articles (09/2008 - 08/2004)|
|5.||Park, Woo Hyun: 3 articles (11/2014 - 10/2012)|
|6.||You, Bo Ra: 3 articles (11/2014 - 10/2012)|
|7.||Salford, Leif G: 3 articles (01/2013 - 11/2007)|
|8.||Widegren, Bengt: 3 articles (01/2013 - 11/2007)|
|9.||Sjögren, Hans-Olov: 3 articles (01/2013 - 11/2007)|
|10.||Shinohara, Fumiaki: 3 articles (07/2009 - 12/2007)|
02/01/2012 - "We observed a significant delay in the growth of mammary tumors in zebularine-treated mice with a statistically significant reduction (P = 0.0135) in total tumor burden at 94 days of age when the mice were sacrificed. "
06/15/2005 - "Three human tumor cell lines were used in this study (MiaPaCa, DU145, and U251) and the methylation status of three genes frequently hypermethylated in tumor cells (RASSF1A, HIC-1, and 14-3-3sigma) was determined as a function of zebularine exposure. "
12/01/2004 - "Further studies exploring the effectiveness of zebularine in a variety of settings could allow the development of novel therapies for cancer."
10/01/2012 - "Zebularine inhibits the growth of HeLa cervical cancer cells via cell cycle arrest and caspase-dependent apoptosis."
02/01/2012 - "After 48 days of zebularine treatment, the tumors were predominantly necrotic compared with untreated animals. "
|2.||Brain Injuries (Brain Injury)
|3.||T-Cell Lymphoma (Lymphoma, T Cell)
01/01/2012 - "Epigenetic changes by zebularine leading to enhanced differentiation of human promyelocytic leukemia NB4 and KG1 cells."
02/01/2009 - "These findings provide a rationale to investigate 5-AZA-CdR in combination with zebularine in patients with advanced leukemia."
12/01/2012 - "In this study, we have observed the antileukemic action of two diverse DNMT inhibitors, the nucleoside agent zebularine and the non-nucleoside agent RG108, in human promyelocytic leukemia (PML) HL-60 cells. "
01/01/2012 - "We evaluated zebularine, a stable and low-toxic cytidine analog, effects on human promyelocytic leukemia cell lines, NB4 and KG1. "
12/01/2012 - "The results confirmed the utility of zebularine and RG108 in combinations with RA and HDAC inhibitors to reinforce differentiation effects in promyelocytic leukemia."
|5.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
06/01/2014 - "This study illustrates the effect of zebularine on human squamous cell carcinoma (SCC-9 and SCC-25) in vitro. "
07/01/2009 - "Zebularine suppresses the apoptotic potential of 5-fluorouracil via cAMP/PKA/CREB pathway against human oral squamous cell carcinoma cells."
07/01/2008 - "Zebularine-induced reduction in VEGF secretion by HIF-1α degradation in oral squamous cell carcinoma."
12/01/2007 - "Epigenetic regulation of chemosensitivity to 5-fluorouracil and cisplatin by zebularine in oral squamous cell carcinoma."
|1.||DNA (Deoxyribonucleic Acid)
|7.||Azacitidine (5 Azacytidine)
|8.||A-Form DNA (A-DNA)
|9.||Histone Deacetylase Inhibitors
|1.||Drug Therapy (Chemotherapy)
|2.||Heterologous Transplantation (Xenotransplantation)