pholcodine

05/01/2023 - "Pholcodine-containing cough and cold medicines: withdrawal from UK market as a precautionary measure. "
01/01/2016 - "Differences in sensitization to NMBAs are partly explained by cross sensitization to pholcodine, an ingredient in cough-medicines available in some countries. "
03/01/2013 - "[New insights into the role of pholcodine in the treatment of cough in 2013?]."
08/01/2009 - "Eventually, a cough syrup containing pholcodine emerged as the most likely suspect. "
04/01/2005 - "Several household chemicals contained SUX and/or MOR activity, but the only difference between Norway and Sweden was cough mixtures containing pholcodine (PHO). "

04/04/2023 - "[Efficacy of compound pholcodine syrup and compound codeine phosphate oral solution on lung cancer-related cough]."
04/04/2023 - "Objective: To assess the clinical efficacy of compound pholcodine syrup and compound codeine phosphate oral solution on lung cancer-related cough. "
04/04/2023 - "Conclusions: Both compound pholcodine syrup and compound codeine phosphate oral solution are effective in treating lung cancer-related cough with similar antitussive effectiveness. "

01/01/2023 - "The aim of this study was to assess the relationship between pholcodine exposure and NMBA-related anaphylaxis. "
05/01/2012 - "Based on the results of published studies that pointed to a connection of the use of pholcodine and perioperative anaphylactic reaction, pholcodine was withdrawn from the Norwegian market and subsequent research revealed a reduction of anaphylactic reactions in that country. "
01/01/2023 - "Patients exposed to pholcodine 12 months before NMBA exposure have a significantly higher risk of an NMBA-related anaphylaxis. "
01/01/2023 - "ALPHO was a multicentre case-control study, comparing pholcodine exposure within a year before anaesthesia between patients with NMBA-related perioperative anaphylaxis (cases) and control patients with uneventful anaesthesia in France. "
01/01/2023 - "Pholcodine, perioperative anaphylaxis, and the European Medicines Agency: finally the decision to remove pholcodine from the market in the European Union."

01/01/2022 - "Gender-specific decline in perioperative allergic reactions in Norway after withdrawal of pholcodine."
07/01/2014 - "This review aims to explore the evidence linking pholcodine exposure to NMBA hypersensitivity and discuss the implications for our understanding of the pathophysiology of these reactions. "
07/01/2014 - "While such observations are compelling in their suggestion of a relationship between pholcodine exposure and NMBA hypersensitivity, important questions remain regarding the mechanisms by which pholcodine is able to sensitize against NMBAs and whether there are other, as yet unidentified, agents that can elicit similar hypersensitivity reactions. "
08/01/2012 - "A recent hypothesis concerning a link between pholcodine exposure and allergic reactions to NMBAs is under investigation. "
06/01/2011 - "Even though the 'pholcodine hypothesis' has been suggested to explain the occurrence of NMBA-induced allergy, this concept remains unclear. "

03/01/2014 - "Opioid non-IgE mediated effects in a BAT assay on drug hypersensitivity to pholcodine."
08/28/2013 - "Opioid non-IgE mediated effects in a BAT assay on drug hypersensitivity to pholcodine."