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phenylurethane
Also Known As:
ethyl N-phenylcarbamate; ethylcarbanilate
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Carboxylic Acids: 973
Acyclic Acids
Carbamates: 945
Urethane: 2067
phenylurethane: 4
Phenylcarbamates: 7
phenylurethane: 4
Related Diseases
1.
Methemoglobinemia
05/01/1975 - "
It was found that by a single administration, methemoglobinemia was induced by phenylhydroxylamine (PHA), nitrobenzene (NB), aniline (A), 2-chloro-A (2-Cl-A), 3-Cl-A, 4-Cl-A, acetanilide (AA), phenacetin (PA), N-(4-chlorophenyl)ethylurethane (CPU), hydroxylamine (HA) and sodium nitrite (SN), and was not observed with phenylurethane, HPU, methylhydroxylamine (MHA), methylamine and nitromethane (NM).
"
2.
Leukemia
09/08/1949 - "
[Childhood leukemia treated with phenylurethane].
"
3.
Chromosome Aberrations (Chromosome Abnormalities)
01/01/1978 - "
The effects of spindle inhibitors and of protein synthesis inhibitors on segmentation mitoses allow us to classify them into six groups : 1. Colchicine type : destruction of the whole achromatic apparatus and centrospheres without storing of dense bodies; 2. Quinoline type : same effect on the achromatic apparatus, but blocked centrospheres with accumulation of dense bodies; 3. Chloralhydrate type : Incomplete destruction of achromatic apparatus, spindle residue which maintains the chromosomes in a star shape, inactive centrospheres sequestered by the reticulum, but without accumulation of dense bodies; 4. Phenylurethane type : Incomplete and reversible action, which leads to easy production of pluripolar mitoses; 5. Carboxylic acid type : dissociation of the spindle, sometimes with blocking of the centrosphere, together with profound chromosome changes without primitive breaks; the intensity and quality of their action is related to the number of carbon atoms in the acid considered; 6. Protein synthesis inhibitor type : (cycloheximide, pederin) characterized by a stop of the nuclear cycle at telo-prophase when the action is sufficient, chromosome abnormalities, sometimes, reduced to strings of beads, and freeing of asters; at weaker concentrations mitosis is possible, but the congression of chromosomes at the equator is abnormal because of functional disturbance of the kinetochores.
"
4.
Carcinoma (Carcinomatosis)
02/01/1954 - "
[Effect of phenylurethane on growth of Ehrlich carcinoma in mice].
"
Related Drugs and Biologics
1.
Hydroxylamine (Hydroxylamine Hydrochloride)
2.
Sodium Nitrite
3.
Protein Synthesis Inhibitors
4.
Phenacetin
5.
Cycloheximide (Cicloheximide)
6.
Colchicine
7.
Carboxylic Acids
8.
Carbon
9.
Acids
10.
acetanilide (acetanilid)