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phenyltoloxamine

RN given refers to parent cpd; structure

Also Known As:

N,N-dimethyl-2-(alpha-phenyl-o-tolyloxy)ethylamine; phenyltoloxamine hydrochloride

Networked: 12 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzhydryl Compounds
        phenyltoloxamine: 12

Experts

1.	Capella-Peiró, E: 1 article (04/2001)
2.	Esteve-Romero, J: 1 article (04/2001)
3.	García-Alvarez-Coque, M C: 1 article (04/2001)
4.	Gil-Agustí, M: 1 article (04/2001)
5.	Monferrer-Pons, L: 1 article (04/2001)

Related Diseases

1.	Pain (Aches) 07/01/1984 - "In this factorial study, 148 outpatients with pain after oral surgery were randomly assigned, on a double-blind basis, a single oral dose of acetaminophen 650 mg, phenyltoloxamine 60 mg, a combination of acetaminophen 650 mg with phenyltoloxamine 60 mg, or placebo. " 07/01/1989 - "The results of this study demonstrate that 60 mg phenyltoloxamine produces significant augmentation of the analgesic activity of 650 mg acetaminophen in postepisiotomy pain."
2.	Asthma (Bronchial Asthma) 07/01/1961 - "A racephedrine-phenyltoloxamine-containing compound (Ephoxamine) in the treatment of bronchial asthma." 11/01/1959 - "Phenyltoloxamine-recephedrine (ephoxamine) in the symtomatic therapy of bronchial asthma." 10/01/1963 - "DEXAMETHASONE-PHENYLTOLOXAMINE IN BRONCHIAL ASTHMA."
3.	Cough 11/25/1977 - "The antitussive effect of two different drugs A (Codeine, Phenyltoloxamine) and B (Dihydrocodeine, Remedacen) was compared in a double blind clinical trial by measuring the frequency and strength of cough attacks for 7 hours. " 04/01/2001 - "The chromatographic behaviour of binary and ternary mixtures of several phenethylamines (phenylephrine, phenylpropanolamine, ephedrine, pseudoephedrine and methoxyphenamine) and antihistamines (pheniramine, carbinoxamine, doxylamine, chlorpheniramine, dexchlorpheniramine, dexbrompheniramine, diphenhydramine, tripolidine, azatadine and phenyltoloxamine), found in cough-cold pharmaceutical preparations, was studied using C8, C18 and cyano columns, micellar mobile phases of sodium dodecyl sulfate (SDS) and pentanol and UV detection. "
4.	Allergic Rhinitis 09/01/1978 - "A dose-and-time related-effect of oral phenyltoloxamine citrate, a Class I, H1 antihistamine compound, has been demonstrated against allergen-induced wheal-and-erythema skin reactions among 10 adults with a diagnosis of allergic rhinitis and seasonal pollinosis. "
5.	Ovarian Neoplasms (Ovarian Cancer) 01/01/1997 - "With regard to the inhibition of human ovarian cancer cell proliferation, phenyltoloxamine and L-histidinol were 5-2500-fold less cytotoxic than DPPE. "

Related Drugs and Biologics

1.	Acetaminophen (Paracetamol)
2.	Analgesics (Analgesic Drugs)
3.	Phenylpropanolamine (Dexatrim)
4.	Phenylephrine (Neo-Synephrine)
5.	Histamine Antagonists (Antihistamines)
6.	Chlorpheniramine (Chlorphenamine)
7.	Pseudoephedrine
8.	Citric Acid (Citrate)
9.	Nasal Decongestants (Decongestants)
10.	Talc

Related Therapies and Procedures

1.	Oral Surgery (Maxillofacial Surgery)
2.	Therapeutics
3.	Intravenous Injections