|1.||Zhan, Chang-Guo: 2 articles (06/2014 - 01/2014)|
|2.||Hou, Shurong: 2 articles (06/2014 - 01/2014)|
|3.||Zhan, Max: 2 articles (06/2014 - 01/2014)|
|4.||Zheng, Fang: 2 articles (06/2014 - 01/2014)|
|5.||Zheng, Xirong: 1 article (06/2014)|
|1.||Cocaine-Related Disorders (Cocaine Addiction)
01/01/2014 - "Further kinetic modelling has suggested that CocH3 with an identical concentration with that of the endogenous BChE in human plasma can effectively eliminate both cocaine and norcocaine in a simplified kinetic model of cocaine abuse."
06/15/2014 - "Further kinetic modelling has suggested that E12-7 with an identical concentration as that of the endogenous BChE in human plasma can effectively eliminate (-)-cocaine, cocaethylene and norcocaine in simplified kinetic models of cocaine abuse and overdose associated with the concurrent use of cocaine and alcohol."
03/01/1994 - "The psychostimulant drug of abuse, cocaine (benzoylecgonine methyl ester), is rapidly metabolized by cleavage of its two ester groups, to give benzoylecgonine (BE) and ecgonine methyl ester, and by N-demethylation, to give N-norcocaine (NC). "
11/01/1995 - "Norcocaine infusion resulted in earlier onset of convulsions and respiratory arrest in conscious rats than cocaine and earlier onset of circulatory arrest. "
07/01/1980 - "Cocaine was shown to significantly increase locomotor activity at doses of 20 and 40 mg/kg, while norcocaine had no effect at these doses and produced convulsions and death at 60 and 80 mg/kg. Both compounds significantly reduced food consumption at one or more of the doses tested. "
11/01/1995 - "Equimolar quantities of cocaine, norcocaine, benzoylecgonine, and ecgonine methyl ester were infused in conscious rats to determine onset of convulsions and respiratory arrest. "
11/01/1995 - "Pentobarbital anesthesia enhanced the respiratory depression and suppressed or delayed the onset of convulsions from norcocaine and cocaine infusion. "
|3.||Ganglion Cysts (Ganglion)
06/01/1999 - "There were no gender-related differences in the doses of norcocaine required to produce circulatory collapse; however, there were significant gender-related differences in the norcocaine tissue-to-plasma concentration ratios (T:P ratios). "
06/01/1999 - "In contrast, female rats had a greater percentage of norcocaine in the plasma at circulatory collapse after acute cocaine administration. "
06/01/1999 - "Arterial blood samples as well as heart, liver, and brain tissues were obtained at circulatory collapse for the measurement of concentrations of norcocaine as well as cocaine and its major metabolites. "
06/01/1999 - "Norcocaine or cocaine was administered intravenously at a rate of 2 mg/kg/min until circulatory collapse. "
|5.||Respiratory Insufficiency (Respiratory Failure)
|1.||Cocaine (Cocaine HCl)
|2.||ecgonine methyl ester