morin

10/01/2022 - "The current study assessed the ameliorative effects of morin on MT-induced testicular damage with the investigation of its mechanism and the potential involvement of oxidative stress, inflammation, apoptosis and endoplasmic reticulum stress in such protection. "
01/01/2018 - "In conclusion, this study suggested that morin attenuated IL-1β-induced inflammation by activating the Nrf2 signaling pathway."
01/01/2017 - "Although the previous trials of inflammation have indicated that morin hydrate (MO) hold considerable promise, understanding the distinct mechanism of MO against inflammation remains a challenge. "
12/01/2022 - "In conclusion, Morin reduced the Dox-induced vascular inflammatory by moderating the miR-188-5p/PTEN/AKT/NF-κB pathway, indicating that Morin might be a therapeutic agent for overcoming the Dox-induced vascular inflammation."
12/01/2022 - "Morin Inhibits Dox-Induced Vascular Inflammation By Regulating PTEN/AKT/NF-κB Pathway."

04/29/2023 - "Taken together, our study shows that the anti-tumor effect of morin/Dox co-treatment is due to the suppression of FOXM1 and attenuation of EGFR/STAT3 signaling pathways in MDA-MB-231 TNBC cells, which suggests that morin offers a means of improving therapeutic efficacy in TNBC patients."
01/01/2016 - "In conclusion, this study suggested that morin inhibits cancer cell adhesion to HUVECs by reducing VCAM1, and EMT by targeting Ncadherin, and that it features antimetastatic activity in vivo. "
01/01/2012 - "This study aims to understand the experience of adolescents with cancer, family and the health team regarding death in the healthcare context, in the light of Edgar Morin's proposed theoretical framework of complexity. "
03/08/2022 - "Our results revealed that NPs kill the cancer cells with greater efficiency than free morin and the morin-Cu(II) complex. "
11/25/2021 - "(Funded by the Morin Family Fund for Pediatric Cancer and Alex's Lemonade Stand Foundation.)."

05/01/2012 - "Morin augments anticarcinogenic and antiproliferative efficacy against 7,12-dimethylbenz(a)-anthracene induced experimental mammary carcinogenesis."
05/01/2012 - "Thus, this study reveals the possible beneficial effect of morin as chemopreventive agent against the oxidative stress induced during mammary carcinogenesis."
01/27/2010 - "Morin fosters apoptosis in experimental hepatocellular carcinogenesis model."
08/01/1999 - "These results indicate that morin could exert a weak chemopreventive effect on large bowel tumorigenesis induced by AOM when fed during the post-initiation phase."
01/01/2019 - "Morin treatment may be envisaged as a system to increase the sensitivity to chemotherapy and to prevent carcinogenesis."

05/01/2012 - "Morin (3,5,7,2',4'-pentahydroxyflavone), a member of the flavanol group, has been shown to possess chemopreventive potential against hepatocellular and colon cancer in experimental animals. "
10/12/2022 - "Further, the immunofluorescence results have also shown a reduction in PUM1 expression in colon cancer cell lines after morin treatment. "
10/12/2022 - "We found that morin has significantly reduced colon cancer cell proliferation, colony formation, migration, and colonospheroid formation in a dose-dependent manner. "
10/12/2022 - "Morin inhibits colon cancer stem cells by inhibiting PUM1 expression in vitro."
02/01/2009 - "Our findings suggest that morin (50mg/kg b.w.) may be a possible chemopreventive agent against colon cancer."

11/16/2023 - "For 10 days, rats received oral doses of morin (50 and 100 mg/kg body weight). "
11/01/2023 - "Forty rats were divided into five groups (n = 8) as follows: control received the vehicle, morin was orally administered 30/mg/kg body weight (MRN30), the AFB1 was administered orally at a dose of 2.5 mg/kg, twice on days 12 and 14 of the experiment for the 3rd, 4th, and 5th groups., AFB1-MRN15 was orally given morin at a dose of 15 mg/kg body weight, and AFB1-MRN30 orally received morin at 30 mg/kg body weight. "
04/01/2023 - "Rats were subjected to oral treatment of morin (50 and 100 mg/kg body weight) for 10 days. "
11/15/2020 - "Testicular damage was evaluated after the rats were treated orally with AC (38.27 mg/kg body weight) alone or with morin (50 and 100 mg/kg body weight) for 10 consecutive days. "
03/01/2020 - "Morin administration in HFD-induced dyslipidemic rats for three weeks, resulted in a significant decrease in the body weight, LW/BW ratio as compared to rats treated with HFD only where the increase in body weight was observed. "