2-methylthiazolidine-4-carboxylic acid

serves as a protective agent against acetaldehyde toxicity by generating free SH groups; RN given refers to (L)-isomer; structure; RN for compound without isomeric designation not available 12/90

Also Known As:

L-2-methylthiazolidine-4-carboxylic acid; MTCA cpd; Z 2196; Z-2196; Z2196

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - 2-methylthiazolidine-4-carboxylic acid: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - 2-methylthiazolidine-4-carboxylic acid: 1

Related Diseases

Fibrosis (Cirrhosis)

04/01/1990 - "Histopathology of PBS + Bleomycin hamsters showed a diffuse mixed mononuclear alveolitis, multifocal fibrosis and peribronchiolar fibrosis, whereas Z2196 + Bleomycin hamsters showed notably less alveolitis and fibrosis.(ABSTRACT TRUNCATED AT 250 WORDS)"
04/01/1990 - "The cysteine pro-drug Z2196 ((2RS, 4R)-2-methylthiazolidine carboxylic acid) and two drugs with methyl esters attached to Z2196 (Z2197 and Z2199) were evaluated for antifibrotic effects in the hamster bleomycin model of lung fibrosis. "

Related Drugs and Biologics

1.	Prodrugs
2.	Esters
3.	Cysteine (L-Cysteine)
4.	Carboxylic Acids
5.	Bleomycin (Blenoxane)
6.	Z 2199
7.	Z 2197