Lipofundin

used in treatment of nutritional disturbances contains 50.0 g sorbitol & 15.0 g phosphatide emulsifier as a 5 or 10 % fatty emulsion in water; use of a 20% emulsion has been reported adversely

Networked: 30 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Griñán, Tania: 2 articles (01/2014 - 03/2012)
2.	Pérez, Arlenis: 2 articles (01/2014 - 03/2012)
3.	Soto, Yosdel: 2 articles (01/2014 - 03/2012)
4.	Martínez-Sánchez, Gregorio: 2 articles (02/2013 - 01/2012)
5.	Noa, Miriam: 2 articles (03/2012 - 09/2005)
6.	Jung, Ja Rang: 1 article (01/2020)
7.	Kim, Ha Yan: 1 article (01/2020)
8.	Kim, Hyun Joo: 1 article (01/2020)
9.	Kim, Hyun Soo: 1 article (01/2020)
10.	Lynch, Carl: 1 article (01/2020)

Related Diseases

1.	Granuloma 03/01/1996 - "At the 11th day, lipofundin was injected intraperitoneally for 8 days to induce formation of foam cells in the granuloma. " 09/01/2005 - "Previous studies have shown that policosanol prevents lipofundin-induced atherosclerotic lesions in rabbits and rats, including foam cell formation, as well as the development of foam cells in carrageenan-induced granulomas in rats. " 09/01/2007 - "Policosanol is a cholesterol-lowering drug isolated from sugar cane wax with concomitant antiplatelet effects that prevents lipofundin-induced atherosclerotic lesions in rabbits and rats, including foam cell formation, and also reduces foam cell formation in carrageenan-induced granulomas in rats, while it inhibits proliferation of smooth muscle cells induced in rabbit cuffed artery. "
2.	Arteriosclerosis 04/01/1986 - "[Recent studies on a lipofundin-induced arteriosclerosis model]." 01/01/1987 - "The Lipofundin arteriosclerosis model developed in our laboratory is present together with the mechanism of development of sclerotic vascular lesions and the primary role of permeability changes in the whole process. " 04/01/1986 - "[Arteriosclerosis developing in rabbits after lipofundin administration]."
3.	Cardiotoxicity 01/01/2023 - "This study aimed to examine the effect of Lipofundin MCT/LCT, an LE, on the cardiotoxicity caused by CQ in H9c2 rat cardiomyoblasts and elucidate the underlying cellular mechanism. " 01/01/2023 - "Collectively, these results suggest that LE (Lipofundin MCT/LCT) inhibits the cardiotoxicity and late apoptosis induced by CQ toxicity via the intrinsic mitochondrial apoptotic pathway that is associated with direct inhibition of ROS production."
4.	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 06/01/2012 - "Sixty-four adult patients with gastrointestinal diseases were randomly assigned to receive isocaloric and isonitrogenous total parenteral nutrition with an ω-3 fatty acid-enriched emulsion (Lipoplus; study group, n = 32) or medium-chain triacylglycerols/long-chain triacylglycerols (Lipofundin; control group, n = 32) for 5 d after surgery. "
5.	Atherosclerosis 01/01/2014 - "Atherosclerosis was induced in NZW rabbits (n = 14) by the administration of Lipofundin 20% using PBS-receiving animals as control (n = 8). " 03/01/2012 - "Moreover, subcutaneous immunization of New Zealand White rabbits (n=19) with chP3R99 mAb (100 μg, 3 doses at weekly intervals) prevented Lipofundin-induced atherosclerosis (2 mL/kg, 8 days) with a 22-fold reduction in the intima-media ratio (P<0.01). " 01/01/2012 - "Due to the importance of these phenomena as risk factors for atherogenesis, we suggest that Lipofundin induces atherosclerosis mainly through these mechanisms." 07/01/1981 - "Considering the above mentioned facts Lipofundin model seems to be particularly useful for testing medicaments used in the therapy of atherosclerosis."

Related Drugs and Biologics

1.	Emulsions
2.	Triglycerides (Triacylglycerol)
3.	Carrageenan
4.	policosanol
5.	Fatty Acids (Saturated Fatty Acids)
6.	Lipids
7.	phospholipid emulsion soybean oil (Intralipid)
8.	SMOFlipid
9.	Soybean Oil
10.	Solvents

Related Therapies and Procedures

1.	Total Parenteral Nutrition
2.	Parenteral Nutrition
3.	Therapeutics
4.	Intravenous Injections
5.	Canes (Cane)