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isoguanine

structure

Also Known As:

2-OH-Ade; 2-hydroxyadenine; 2-oxyadenine; 6-amino-1,3-dihydro-2H-purin-2-one

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Hypoxanthines: 1
        Guanine: 1793
        isoguanine: 2

Experts

1.	Hua, Xiaoting: 1 article (07/2021)
2.	Wang, Fei: 1 article (07/2021)
3.	Wang, Xiaogang: 1 article (07/2021)
4.	Xia, Qingyou: 1 article (07/2021)
5.	Xu, Wei: 1 article (07/2021)
6.	Zhang, Quan: 1 article (07/2021)
7.	Zhao, Ping: 1 article (07/2021)
8.	Nakabeppu, Yusaku: 1 article (04/2006)
9.	Nakatsu, Yoshimichi: 1 article (04/2006)
10.	Sakamoto, Katsumi: 1 article (04/2006)

Related Diseases

1.	Infections 07/10/2021 - "Glycerophosphocholine (GPC), 2-hydroxyadenine (2-OH-Ade), gamma-glutamylcysteine (γ-Glu-Cys), hydroxytolbutamide, and 5-pyridoxolactone glycerophosphocholine were continuously upregulated in BmE cells post BmNPV infection by heat map analysis. "
2.	Autosomal Recessive Colorectal Adenomatous Polyposis 04/01/2006 - "MUTYH deficiency may also increase G:C to T:A transversions through the misincorporation of 2-OH-dATP, especially in the intestinal tract, since MUTYH can excise 2-hydroxyadenine opposite guanine in genomic DNA and the repair activity is selectively impaired by a mutation found in patients with autosomal recessive colorectal adenomatous polyposis."

Related Drugs and Biologics

1.	Guanine
2.	DNA (Deoxyribonucleic Acid)
3.	5-pyridoxic acid lactone
4.	2-hydroxydeoxyadenosine triphosphate
5.	gamma-glutamylcysteine