HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
inicarone
Also Known As:
L 7035; isopropyl-2-isonicotinyl-3-benzofuran; (2-(1-methylethyl)-3-benzofuranyl)-4-pyridinylmethanone
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzofurans: 26
inicarone: 1
Related Diseases
1.
Lewis Lung Carcinoma
10/01/1983 - "
The effect of inicarone (L7035), a potent fibrinolytic, alone or in combination, was investigated on spontaneously metastasizing Lewis lung carcinoma (implanted intramuscularly) to verify whether it could prevent the formation of metastases.
"
2.
Neoplasm Metastasis (Metastasis)
10/01/1983 - "
The effect of inicarone (L7035), a potent fibrinolytic, alone or in combination, was investigated on spontaneously metastasizing Lewis lung carcinoma (implanted intramuscularly) to verify whether it could prevent the formation of metastases.
"
10/01/1983 - "
Moreover, when inicarone was combined with a potent antimetastatic agent, Nocodazole, it was shown to be in competition with the latter agent and totally overshadowed its activity; since inicarone had no antimetastatic effect, the number of metastases rose dramatically.
"
10/01/1983 - "
When administered in combination with cyclophosphamide, an antiproliferative agent, inicarone did not induce any synergism or antagonism, but this combination did not inhibit tumour growth or metastasis spreading.
"
10/01/1983 - "
Its activity was compared to that of warfarin, an anticoagulant: both drugs were inactive when administered in curative treatment and inicarone even enhanced the number of lung metastases.
"
Related Drugs and Biologics
1.
Nocodazole
2.
Warfarin (Coumadin)
3.
Cyclophosphamide (Cytoxan)
4.
Anticoagulants