25-hydroxycholesterol

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52 relevant articles (0 outcomes, 3 trials/studies) found for this Bio-Agent

Description: structure; RN given refers to cpd without isomeric designation

Also Known As:

25-hydroxycholesterol, (3beta)-isomer, 26-(14)C-labeled; 25-hydroxycholesterol, (3beta,20S)-isomer; 5-cholestene-3beta,25-diol; cholest-5-ene-3 beta,25-diol

Bio-Agent Context: Research Results

Polycyclic Compounds: 58

Hydroxycholesterols: 1

25-hydroxycholesterol: 52

Cholestenes

Cholesterol: 31213

Hydroxycholesterols: 1

25-hydroxycholesterol: 52

Hydroxycholesterols: 1

25-hydroxycholesterol: 52

Experts

1.	Sato, Hiroshi: 1 article (12/2005)
2.	Sugiura, Hisashi: 1 article (12/2005)
3.	Tanaka, Toshihiro: 1 article (12/2005)
4.	Yamamoto, Kazuo: 1 article (12/2005)
5.	Bai, Bingxue: 1 article (12/2005)
6.	Gueguen, Y: 1 article (01/2001)
7.	Bertrand, P: 1 article (01/2001)
8.	Ferrari, L: 1 article (01/2001)
9.	Batt, A M: 1 article (01/2001)
10.	Siest, G: 1 article (01/2001)

Related Diseases

1.	Atherosclerosis (Atheroma) 02/01/1982 - "Distribution of 25-hydroxycholesterol in plasma lipoproteins and its role in atherogenesis" 09/15/2006 - "In the present study, we investigated the cytotoxic effects of 7beta-hydroxycholesterol (7betaOH), 7-ketocholesterol (7keto), 25-hydroxycholesterol (25OH), and 27-hydroxycholesterol (27OH) on U937 monocytic cells, both individually and in atheroma-relevant mixtures mimicking the oxysterol composition reported in human atheroma lesions" 03/01/1989 - "The imbalance between acyl CoA cholesterol acyl transferase and hydrolase activities induced by 25-hydroxycholesterol could result in cholesteryl ester accumulation by arterial smooth muscle cells, which may be associated with atherosclerosis." 01/01/1991 - "Some cholesterol oxides, notably cholestane-3 beta, 5 alpha, 6 beta-triol and 25-hydroxycholesterol, have been shown to cause injury to vascular endothelial and smooth muscle cells, to alter LDL receptor function, to enhance cholesteryl ester accumulation, to inhibit prostacyclin production, and to induce experimental atherosclerosis alone or in combination with cholesterol" Get all the results and reference details, order at left...
2.	Mastocytoma 09/01/1994 - "The objective of this study was to investigate the effects of oxysterols (OS), namely 5 alpha-hydroxy-6-ketocholestanol, 6-ketocholestanol and 25-hydroxycholesterol, on specific cell-mediated cytotoxicity by C57BL/6 spleen cells against P815-X2 (a DBA/2 mastocytoma) target cells" 08/01/1984 - "The mechanism whereby 25-hydroxycholesterol, an inhibitor of the synthesis of cholesterol, depresses DNA synthesis in cycling P815 mastocytoma cells was investigated" Get all the results and reference details, order at left...
3.	Allergic Contact Dermatitis 02/01/2003 - "In this study, the anti-inflammatory effects of two oxysterols, 22(R)-hydroxy-cholesterol (22ROH) and 25-hydroxycholesterol (25OH), and a nonsterol activator of LXR, GW3965, were examined utilizing models of irritant and allergic contact dermatitis" Get all the results and reference details, order at left...
4.	Hepatocellular Carcinoma (Hepatoma) 06/07/2002 - "In transfected hepatoma cells, 25-hydroxycholesterol increased murine Cyp7a1 gene promoter activity, whereas the human CYP7A1 gene promoter was unresponsive" 05/01/1995 - "Movement of 25-hydroxycholesterol from the plasma membrane to the rough endoplasmic reticulum in cultured hepatoma cells." 04/01/1991 - "Activation of the silent endogenous cholesterol-7-alpha-hydroxylase gene in rat hepatoma cells: a new complementation group having resistance to 25-hydroxycholesterol." 05/01/2000 - "Previously, we have demonstrated that treatment of rat AH136B ascites hepatoma cells with 25-hydroxycholesterol (25-OH) induces apoptosis" 02/01/2000 - "7beta-Hydroxycholesterol (7beta-OHC) and 25-hydroxycholesterol, both of which are commonly found in foods, were investigated for their abilities to induce apoptosis in a human monocytic blood cell line, U937, and in the human hepatoma cell line, HepG2 cells" Get all the results and reference details, order at left...
5.	Neoplasms (Cancer) 05/01/2000 - "These findings suggest that local combined treatment with 25-hydroxycholesterol and low-dose TNF can induce synergistic anti-tumor effects." 09/01/1998 - "Macrophage inhibition of lymphocyte and tumor cell growth is mediated by 25-hydroxycholesterol in the cell membrane." 03/01/1986 - "The kinetics of cell cycle progression in continuously proliferating 3T3 fibroblasts and two tumor transformed derivatives (3T6 and SV 3T3 cells) following treatment by growth-factor deprivation (serum starvation) or 25-hydroxycholesterol were studied" 04/01/2004 - "To investigate whether oxysterols can regulate StAR expression, two steroidogenic cell lines, mouse Y1 adrenocortical and MA-10 Leydig tumor cells, were treated with various oxysterols and steroids, including 25-hydroxycholesterol (25 OHC), 22(R)OHC and 20alphaOHC" 01/01/1991 - "25-Hydroxycholesterol and 20 alpha-hydroxycholesterol are potent suppressors of generation and proliferation of tumor-specific cytotoxic T lymphocytes" Get all the results and reference details, order at left...
35 Diseases and 52 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	cholest-5-en-3 beta,7 alpha-diol
2.	7-ketocholesterol
3.	GW 3965
4.	27-hydroxycholesterol
5.	6-ketocholestanol
6.	Cholesterol
7.	Messenger RNA (mRNA)
8.	Interleukin-8 (Interleukin 8)
9.	LDL Receptors (LDL Receptor)
10.	Lipoproteins (Lipoprotein)
53 Drugs and Important Bio-Agents and 46 more articles analyzed in the Research Interface, order at left...

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