galacturonic acid

N1 same as NM; RN given refers to parent cpd with unspecified isomeric designation

Also Known As:

(D)-galacturonic acid; (DL)-galacturonic acid; D-galacturonic acid; DL-galacturonic acid; galacturonic acid, (D)-isomer; galacturonic acid, (alpha-D)-isomer; galacturonic acid, D-; galacturonic acid, DL-; galacturonic acid, calcium, sodium salt, (D)-isomer; galacturonic acid, monosodium salt, (D)-isomer

Networked: 31 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	He, Gui-Hua: 1 article (01/2021)
2.	Huang, Sui-Ping: 1 article (01/2021)
3.	Wu, Yu-Yao: 1 article (01/2021)
4.	Ye, Zhen-Hao: 1 article (01/2021)
5.	Zhang, Wang: 1 article (01/2021)
6.	Zheng, Yi-Feng: 1 article (01/2021)
7.	Zhong, Zi-Shao: 1 article (01/2021)
8.	Chen, Weidong: 1 article (12/2020)
9.	Ellur, Vishnutej: 1 article (12/2020)
10.	Peng, Hao: 1 article (12/2020)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2021 - "D-galacturonic acid ameliorates the intestinal mucosal permeability and inflammation of functional dyspepsia in rats." 01/01/2020 - "However, galacturonic acid is also sensed as a signal through ExuR to modulate the expression of the genes encoding a molecular syringe known as a type III secretion system, leading to infectious colitis and inflammation. "
2.	Melanoma (Melanoma, Malignant) 08/01/2018 - "Depigmentation efficacy of galacturonic acid through tyrosinase regulation in B16 murine melanoma cells and a three-dimensional human skin equivalent."
3.	Dyspepsia (Indigestion) 01/01/2021 - "D-galacturonic acid ameliorates the intestinal mucosal permeability and inflammation of functional dyspepsia in rats."
4.	Neoplasms (Cancer) 11/01/2018 - "Anti-cancer activity of di- and tri-organotin(IV) compounds with D-(+)-Galacturonic acid on human tumor cells." 07/01/2015 - "Modified pectin is a polysaccharide rich in galacturonic acid altered by pH adjustment and thermal treatment used especially as an anti-cancer agent. " 05/12/2000 - "Aplysia gonad lectin (AGL), which has been shown to stimulate mitogenesis in human peripheral lymphocytes, to suppress tumor cells, and to induce neurite outgrowth and improve cell viability in cultured Aplysia neurons, exhibits a peculiar galacturonic acid/galactose specificity. " 01/01/1989 - "The rate of effector cell/tumor cell conjugate formation in the presence of V. album extracts, as well as the abrogation of both activities by pretreatment of V. album extracts with exoglycosidases specific for sugars other than galacturonic acid indicated an action of the NK cytotoxicity-enhancing component on the basis of a bridging mechanism. " 01/01/1990 - "Using a specifically adapted agglutination assay, the saccharide residues of the rhamnogalacturonan interacting with NK cells and tumor cells could be identified by the formation of homologous cell conjugates induced by acetylated rhamnose or acetylated mannose conjugated to dextran and by polygalacturonic acid: terminal acetylated rhamnose or acetylated mannose bound only to NK cells in a dose-dependent manner but not to K562 tumor cells, and terminal galacturonic acid only to K562 tumor cells but not to NK cells. "
5.	Infections 01/01/2020 - "Here, we show that enterohaemorrhagic Escherichia coli and Citrobacter rodentium, its surrogate in a mouse infection model, sense galacturonic acid to initiate a multi-layered program towards successful mammalian infection. " 12/01/2020 - "The D-galacturonic acid catabolic genes are transcriptionally induced by either polygalacturonic acid in the culture media or during host infection. " 04/01/2016 - "Quantitative real-time reverse transcription-polymerase chain reaction (RT-PCR) revealed that endoPGs pg1 and pg5 and exoPGs pgx4 and pgx6 are expressed at significant levels during growth on citrus pectin, polygalacturonic acid or the monomer galacturonic acid, as well as during the infection of tomato plants. " 10/01/1991 - "Of the other sugars tested D-glucose, L-rhamnose, D-xylose and D-galacturonic acid, the main components of plant cell wall polysaccharides, remarkedly potentiated the vir-inducing activity of AS, indicating the cooperative action of the signal compounds and sugars in Agrobacterium infection to plants."

Related Drugs and Biologics

1.	Monophenol Monooxygenase (Tyrosinase)
2.	Glucose (Dextrose)
3.	Rhamnose
4.	Galactose (Galactopyranose)
5.	Pectins
6.	Arabinose (L-Arabinose)
7.	Polysaccharides (Glycans)
8.	Mannose (D-Mannose)
9.	polygalacturonic acid (pectic acid)
10.	Glucuronic Acid (Glucuronate)