fucoidan

11/23/2021 - "Fucoidan-Based Nanoparticles with Inherently Therapeutic Efficacy for Cancer Treatment."
07/01/2020 - "Fucoidan usage as soluble agent presents promising results herein described for different types of cancer. "
01/01/2014 - "Despite a number of in vitro and in vivo studies reporting the efficacy of fucoidan in treating various cancers, few studies have measured the efficacy of dietary fucoidan (DF) in combination with cancer drugs. "
01/15/2024 - "Rationally designed clinical trials for the critical evaluation of fucoidan against different cancers will be valuable to reap full benefits."
01/15/2024 - "We have set spotlight on fucoidan-mediated tumor suppressive effects in cell cultures studies and tumor-bearing rodent models. "

04/01/2023 - "Concerning phagocytosis, however, the inflammation-induced reduction was not improved by FV fucoidan. "
12/11/2021 - "These observations on various fucoidan extracts offer insight into strategies that improve their efficacy against inflammation-related pathology. "
01/31/2021 - "Low molecular weight fucoidan fraction ameliorates inflammation and deterioration of skin barrier in fine-dust stimulated keratinocytes."
08/29/2023 - "This study suggested that fucoidan had anti-inflammatory potentials and thus can be used as a promising drug candidate against inflammation.Communicated"
12/23/2022 - "The present study emphasized the effect of low-molecular-weight fucoidan isolated from Sargassum confusum (LMF) against FD-induced inflammation in HaCaT keratinocytes and underneath fibroblasts (HDFs) in an integrated culture model. "

12/01/2008 - "A significant improvement of survival was observed by pretreatment with fucoidan at 100 mg/kg body weight. "
03/01/2011 - "After 3 weeks, fucoidan treatment improved left ventricular ejection fraction (79.04 ± 2.81 vs 65.94% ± 3.22%; P < .01 vs EAM-saline) with a reduced ratio of heart weight to body weight (4.016 ± 0.239 vs 4.975 ± 0.252 mg/g; P < .05 vs EAM-saline) in EAM. "
05/11/2021 - "Up to 56% liquor (7 to 9 mL per kg body weight) was orally administered 1 h after the fucoidan treatment for 20 weeks. "
05/11/2021 - "Here, 20 male rats in each group were treated with fucoidan (150 and 300 mg per kg body weight) by gavage once daily. "
02/21/2018 - "Sixty female Sprague-Dawley rats were randomly assigned to the control group, the model group, and the F1 and F2 groups, which were fed fucoidan at concentrations of 200 and 400 mg per kg bw (body weight), respectively. "

02/21/2018 - "The study suggested the use of fucoidan as an intestinal flora modulator for potential prevention of breast cancer."
10/01/2013 - "In this study, the effect of Fucoidan on the proliferation and apoptosis of human breast cancer MCF-7 cells and the molecular mechanism of Fucoidan action were investigated. "
04/01/2013 - "This study is the first to identify a novel mechanism for fucoidan antitumor activity, namely regulation of the EMT via modulation of TGFR/Smad-dependent signaling, which leads to an inhibition of breast cancer cell growth in vitro and in vivo. "
01/01/2012 - "In this study, we examined the influence of crude fucoidan on mouse breast cancer in vitro and in vivo. "
10/09/2023 - "The MCF-7 breast cancer cells were treated with fucoidan extract from S. "

12/18/2020 - "Collectively, these results suggest that fucoidan may be a promising treatment for obesity and obesity-induced complications."
09/01/2022 - "Sargassum fusiforme fucoidan ameliorates diet-induced obesity through enhancing thermogenesis of adipose tissues and modulating gut microbiota."
06/06/2022 - "Thus, the present study aimed to investigate the possible discrepancy of the anti-obesity effects of fucoidan supplementation in HFD-fed mice models with different gut microbiota communities. "
06/06/2022 - "Previous studies have indicated that fucoidan could resist high-fat-diet (HFD)-induced obesity by modulating the composition of gut microbiota. "
01/01/2022 - "In this study, we applied network pharmacology and systematic bioinformatics analysis, such as gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses, together with molecular docking, to investigate the targets of fucoidan for treating PFOA-associated obesity through the regulation of endoplasmic reticulum stress (ERS). "