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fluorexon (calcein)

structure
Also Known As:
calcein; 2',7'-bis((bis(carboxymethyl)amino)methyl)fluorescein
Networked: 198 relevant articles (4 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Ando, Masayoshi: 6 articles (01/2011 - 01/2007)
2. Hasegawa, Toshiaki: 6 articles (01/2011 - 01/2007)
3. Kataoka, Takao: 5 articles (01/2011 - 01/2007)
4. Weiss, Johanna: 4 articles (11/2015 - 04/2011)
5. Prausnitz, Mark R: 4 articles (03/2014 - 07/2002)
6. Zhao, Ming: 4 articles (04/2012 - 01/2007)
7. Bai, Liming: 4 articles (01/2011 - 01/2007)
8. Ogura, Hirotsugu: 4 articles (01/2011 - 01/2007)
9. Prausnitz, M R: 4 articles (06/2010 - 02/2001)
10. Tomida, Akihiro: 4 articles (01/2008 - 02/2007)

Related Diseases

1. Necrosis
05/01/2013 - "In postconditioned cells, the collapse in ΔΨm as well as the leak of calcein, the increase in mitochondrial Ca(2+), cytosolic Ca(2+) oscillations, contracture and necrosis were significantly reduced. "
05/01/2022 - "All animals successfully established models of femoral head necrosis, and then the difference among the Immunohistochemistry, Quantitative polymerase chain reaction (qPCR) analysis, Enzyme-linked immunosorbent assay, Biomechanical test, etracyclline-calcein double labeling, and Van Gieson staining indices were compared among the four groups. "
05/01/2016 - "ATP/protein, calcein fluorescence/ATP, calcein fluorescence/protein ratios, DAPI fluorescence and protein levels together with morphological and apoptosis/necrosis parameters deciphered subtle changes in cell viability with good between-run precision. "
05/01/2009 - "The effect of melatonin on the activation of caspases was time dependent, reaching a maximum after 12 hr of stimulation, and then decreasing to a minimum after 72 hr. Treatment with melatonin also evoked mitochondrial membrane depolarization and permeability transition pore induction, which caused loss of mitochondrial staining by calcein, and increased cell death by apoptosis/necrosis as demonstrated by propidium iodide positive-staining of cells after 72 hr of stimulation. "
06/10/2022 - "The protective effects of TCT were observed in a general viability assay (calcein ester hydrolysis), in an apoptosis assay (caspase activity), and in necrosis assays (propidium iodide uptake and lactate dehydrogenase release). "
2. Ischemia
3. Thrombosis (Thrombus)
4. Osteoporosis
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Esters
2. Propidium (Propidium Iodide)
3. Calcium
4. Caspases
5. L-Lactate Dehydrogenase (Lactate Dehydrogenase)
6. Phosphorus (Red Phosphorus)
7. Liposomes (Liposome)
8. Proteins (Proteins, Gene)
9. Coloring Agents (Dyes)
10. Fluorescent Dyes (Fluorescent Probes)

Related Therapies and Procedures

1. Lasers (Laser)
2. Quantum Dots (Quantum Dot)
3. Microbubbles
4. Transplantation
5. Therapeutics