etiron

a nitric oxide synthase inhibitor; RN given refers to parent cpd; structure

Also Known As:

2-ethylisothiourea hydrobromide; S-ethylisothiourea; ethylisothiuronium bromide; ethyron; etiron monohydrobromide

Networked: 7 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Thiourea: 362
      - Isothiuronium: 13
        etiron: 7
- Sulfur Compounds: 278
  - Thiourea: 362
    - Isothiuronium: 13
      - etiron: 7

Experts

1.	Cortese-Krott, Miriam M: 1 article (01/2014)
2.	Gladwin, Mark T: 1 article (01/2014)
3.	Gorressen, Simone: 1 article (01/2014)
4.	Gödecke, Axel: 1 article (01/2014)
5.	Kelm, Malte: 1 article (01/2014)
6.	Merx, Marc W: 1 article (01/2014)
7.	Ohlig, Jan: 1 article (01/2014)
8.	Rassaf, Tienush: 1 article (01/2014)
9.	Stern, Manuel: 1 article (01/2014)
10.	van de Sandt, Annette M: 1 article (01/2014)

Related Diseases

1.	Shock 09/01/1996 - "Effects of S-ethylisothiourea, a potent inhibitor of nitric oxide synthase, alone or in combination with a nitric oxide donor in splanchnic artery occlusion shock." 09/01/1996 - "1. The aim of this study was to compare the effects of an intravenous infusion of a potent and non selective nitric oxide synthase inhibitor S-ethylisothiourea (Ethyl-TU) with that of a nitric oxide (NO) donor on the pathological sequelae associated with splanchnic artery occlusion (SAO) shock. "
2.	COVID-19 01/24/2023 - "In this study, the key intermediate N 1, N 3-disubstituted 1,3,5-triazone of ensitrelvir fumaric acid, approved in Japan for the treatment of SARS-CoV-2 infection under the emergency regulatory approval system, was produced from S-ethylisothiourea hydrobromide and aminomethyl triazole with CDI by four-step telescoped strategy including CDI-activated, condensation, CDI-cyclization, and N 1-alkylation. "
3.	Wounds and Injuries (Trauma) 09/01/1973 - "[Combined use of gangliolytics and ethyron for blood circulation control during surgical trauma]."
4.	Ischemia 01/01/2003 - "A nonselective nitric oxide synthase (NOS) inhibitor, N( omega)-nitro-L-arginine methyl ester (L-NAME), and a selective inducible NOS (iNOS) inhibitor, S-ethylisothiourea (EIT), given twice after reperfusion, produced an anxiolytic effect in the elevated plus-maze test 2 days after the ischemia, while only the former produced antianxiety in the social interaction test. "
5.	Infarction (Infarctions) 01/01/2014 - "Application of the NOS inhibitor S-ethylisothiourea hydrobromide was associated with larger infarct size in BC+/EC+, whereas infarct size in BC-/EC+ mice remained unaffected. "

Related Drugs and Biologics

1.	Nitric Oxide Synthase (NO Synthase)
2.	Triazoles
3.	Nitric Oxide (Nitrogen Monoxide)
4.	fumaric acid (sodium fumarate)
5.	ensitrelvir
6.	Nitric Oxide Donors
7.	NG-Nitroarginine Methyl Ester (L-NAME)
8.	Anti-Anxiety Agents (Anxiolytics)
9.	Posterior Pituitary Hormones
10.	Kininogens (Kininogen)

Related Therapies and Procedures

1.	Intravenous Infusions
2.	Intravenous Administration