ethaverine

tetraethyl homolog of papaverine; smooth muscle relaxant; RN given refers to parent cpd; structure

Also Known As:

Ethaquin; Ethquinol; ethaverine hydrochloride; ethylpapaverine; 6,7-diethoxy-1-(3,4-diethoxybenzyl)isoquinoline

Networked: 9 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Opiate Alkaloids: 5944
    - Papaverine: 1160
      - ethaverine: 9
  - Benzylisoquinolines: 151
    - Papaverine: 1160
      - ethaverine: 9
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoquinolines: 34
      - Benzylisoquinolines: 151
        Papaverine: 1160
        ethaverine: 9

Related Diseases

1.	Angina Pectoris 10/01/1954 - "Studies on the use of ethaverine in the treatment of angina pectoris." 04/01/1954 - "Ethaverine in the treatment of angina pectoris." 09/05/1953 - "Ethaverine in the treatment of angina pectoris."
2.	Intermittent Claudication 05/01/1986 - "The effect of ethaverine hydrochloride on exercise tolerance of patients with intermittent claudication was evaluated in a double-blind, placebo-controlled study conducted at three sites. " 05/01/1986 - "It was concluded that ethaverine safely increased distance-to-claudication in patients with intermittent claudication." 05/01/1986 - "Effects of ethaverine hydrochloride on the walking tolerance of patients with intermittent claudication."
3.	Peripheral Vascular Diseases (Peripheral Vascular Disease) 10/01/1974 - "Hemodynamic effects of ethaverine hydrochloride in patients with peripheral vascular disease." 11/01/1991 - "Ethaverine is a derivative of papaverine used in the treatment of peripheral vascular disease and is thought to cause vasodilation by reducing intracellular Ca2+ concentrations in vascular smooth muscle cells. "
4.	Coronary Occlusion 03/01/1978 - "These effects of dipyridamole, carbochromen, pentaerythritol tetranitrate (PETN), papaverine and ethaverine on collateral hemodynamics were investigated in anesthetized dogs 5 weeks after experimental coronary occlusion. "
5.	Melanoma (Melanoma, Malignant) 01/01/1975 - "Chloroquine, ergotamine, ethaverine and chronic abuse of non-narcotic analgesic drugs seem to be responsible for the drug-induced cutaneous neuro-phospholipidosis, whereas the same condition was found in two patients with metastatic bronchogenic carcinoma and malignant melanoma."

Related Drugs and Biologics

1.	Papaverine
2.	Pentaerythritol Tetranitrate (Pentalog)
3.	Narcotics (Narcotic Analgesics)
4.	Ergotamine (Ergotamine Tartrate)
5.	Dipyridamole (Persantine)
6.	Chromonar (Carbocromen)
7.	Chloroquine (Aralen)
8.	Analgesics (Analgesic Drugs)

Related Therapies and Procedures

1.	Therapeutics