|1.||Choi, Yung Hyun: 6 articles (01/2015 - 03/2008)|
|2.||Hyun, Jin Won: 3 articles (10/2015 - 12/2008)|
|3.||Moon, Sung-Kwon: 3 articles (10/2011 - 12/2008)|
|4.||Kim, Wun-Jae: 3 articles (10/2011 - 03/2010)|
|5.||Park, Cheol: 3 articles (03/2010 - 03/2008)|
|6.||Jin, Cheng-Yun: 3 articles (03/2010 - 03/2008)|
|7.||Kwon, Taeg Kyu: 3 articles (03/2010 - 03/2008)|
|8.||Kim, Gi-Young: 3 articles (03/2010 - 03/2008)|
|9.||Gaikwad, Anil Bhanudas: 2 articles (10/2015 - 05/2015)|
|10.||Kadakol, Almesh: 2 articles (10/2015 - 05/2015)|
01/01/2011 - "Esculetin, a phenolic compound, has been shown to inhibit the growth of colon tumors in animal studies. "
03/01/2015 - "Tumor weight was decreased by 20.33, 40.37, and 55.42% with increasing doses of esculetin. "
03/01/2015 - "Esculetin significantly decreased tumor growth in mice bearing Hepa1-6 cells. "
01/01/2015 - "Esculetin (6,7-dihydroxycoumarin): a potential cancer chemopreventive agent through suppression of Sp1 in oral squamous cancer cells."
01/01/2011 - "However, the roles of signaling pathways and cell cycle regulation in the esculetin-induced inhibition of cancer cell growth, remain to be elucidated. "
|2.||Mouth Neoplasms (Oral Cancer)
12/01/2009 - "Combination of esculetin and TRAIL may be a novel treatment strategy for oral cancers."
01/01/2015 - "This indicates that esculetin inhibited cell growth and induced apoptosis by suppressing Sp1 in HN22 and HSC4 cells, suggesting it to be a potent anticancer drug candidate for oral cancer. "
12/01/2009 - "In this study, we showed that esculetin significantly suppressed the growth of oral cancer SAS cells in a dose-dependent manner. "
12/01/2009 - "Esculetin enhances TRAIL-induced apoptosis through DR5 upregulation in human oral cancer SAS cells."
|3.||Cardiac Arrhythmias (Arrythmia)
03/01/2008 - "In the present study, we used human leukemia cells to gain further insight into the mechanism of esculetin-induced anti-proliferative action and apoptosis. "
03/23/2001 - "In the present study, esculetin was found to inhibit the survival of human promyelocytic leukemia HL-60 cells in a concentration-dependent and time-dependent manner. "
03/01/2008 - "These results indicated that the JNK and ERK pathways were key regulators of apoptosis in response to esculetin in human leukemia U937 cells."
03/01/2008 - "Induction of apoptosis by esculetin in human leukemia U937 cells through activation of JNK and ERK."
09/26/2002 - "These results suggest that esculetin can inhibit the growth of human leukemia HL-60 cells by G1 phase cell cycle arrest as a result of inhibited pRb phosphorylation."
|5.||Colonic Neoplasms (Colon Cancer)
10/01/2015 - "The present study examined whether esculetin induces apoptosis in HT-29 colon cancer cells by inducing endoplasmic reticulum (ER) stress. "
01/01/2011 - "The present study suggests a novel mechanism for the Ras/ERK1/2 pathway in esculetin-treated human colon cancer HCT116 cells. "
10/01/2015 - "Taken together, these results suggest that the ER stress response plays an important role in esculetin-induced apoptosis in human colon cancer cells. "
10/01/2015 - "Esculetin induces apoptosis in human colon cancer cells by inducing endoplasmic reticulum stress."
12/01/2013 - "In addition, esculetin effectively decreased viability and inhibited anchorage-independent growth of colon cancer cells. "
|4.||Ouabain (G Strophanthin)
|2.||Fat-Restricted Diet (Diet, Fat Restricted)
|3.||Heterologous Transplantation (Xenotransplantation)
|4.||Traditional Medicine (Folk Remedies)