echinochrome A

red pigment of sea urchin eggs (Arbacia pustulosa)

Also Known As:

2,3,5,6,8-pentahydroxy-7-ethyl-1,4-naphthoquinone; 2-ethyl- 2,5,6,7,8-pentahydroxy-1,4-naphthoquinone; 2-ethyl-3,6,7-trihydroxynaphthazarin; echinochrom; echinochrome 1

Networked: 21 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthoquinones: 418
        echinochrome A: 21
- Quinones: 434
  - Naphthoquinones: 418
    - echinochrome A: 21
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthoquinones: 418
      - echinochrome A: 21

Experts

1.	Fedoreyev, Sergey A: 7 articles (11/2021 - 08/2014)
2.	Mishchenko, Natalia P: 7 articles (11/2021 - 08/2014)
3.	Han, Jin: 6 articles (11/2021 - 08/2014)
4.	Stonik, Valentin A: 5 articles (11/2021 - 08/2014)
5.	Kim, Hyoung Kyu: 4 articles (11/2021 - 08/2014)
6.	Vasileva, Elena A: 3 articles (11/2021 - 06/2019)
7.	Ko, Kyung Soo: 2 articles (11/2021 - 08/2014)
8.	Rhee, Byoung Doo: 2 articles (11/2021 - 08/2014)
9.	Krivoshapko, O N: 2 articles (01/2014 - 03/2012)
10.	Popov, A M: 2 articles (01/2014 - 03/2012)

Related Diseases

1.	Ischemia 11/01/1991 - "The efficacy of echinochrom given after prolonged ischemia, low effective doses, and no adverse effects create prerequisites for using the drug in the clinical setting." 11/01/1991 - "A supplementary administration of echinochrom 5 min after the onset of ischemia failed to contribute to a significant enhancement of its protective effect, suggesting that there is no substantial effect of the agent on ischemic lesion. " 01/12/2023 - "Polyhydroxynaphtoquinone echinochrome A (Ech-A), a natural pigment of marine origin found in the shells and needles of many species of sea urchins, is a potent antioxidant and inhibits acute myocardial ferroptosis after ischemia/reperfusion, but the chronic effect of Ech-A on heart failure is unknown. "
2.	Melanoma (Melanoma, Malignant) 08/29/2022 - "In this study, we investigated the effects of echinochrome A (Ech A) on melanogenesis in the B16F10 murine melanoma cell line. "
3.	Inflammation (Inflammations) 11/30/2022 - "Regulation of Inflammation-Mediated Endothelial to Mesenchymal Transition with Echinochrome a for Improving Myocardial Dysfunction." 05/15/2020 - "Marine Polyhydroxynaphthoquinone, Echinochrome A: Prevention of Atherosclerotic Inflammation and Probable Molecular Targets." 04/23/2021 - "Echinochrome A Treatment Alleviates Fibrosis and Inflammation in Bleomycin-Induced Scleroderma."
4.	Reperfusion Injury 08/21/2014 - "Echinochrome A (Ech A) is a natural pigment from sea urchins that has been reported to have antioxidant properties and a cardio protective effect against ischemia reperfusion injury. " 06/21/2019 - "Histochrome (sodium salt of echinochrome A-a common sea urchin pigment) is an antioxidant drug that has been clinically used as a pharmacologic agent for ischemia/reperfusion injury in Russia. "
5.	Infections 12/12/2022 - "The ability of complexes of κ- and Σ-carrageenans (CRGs)-sulfated polysaccharides of red algae, with echinochrome A (Ech), as well as the liposomal form of the Σ-CRG/Ech complex-to inhibit different stages of HSV-1 infection in Vero cells was studied. " 11/05/2020 - "The ability of sea urchin spinochromes-echinochrome A (EchA) and its aminated analogues, echinamines A (EamA) and B (EamB)-to inhibit different stages of HSV-1 infection in Vero cells and to reduce the virus-induced production of reactive oxygen species (ROS) was studied. "

Related Drugs and Biologics

1.	Antioxidants
2.	Interleukin-13
3.	Reactive Oxygen Species (Oxygen Radicals)
4.	Interleukin-4 (Interleukin 4)
5.	Sodium
6.	Salts
7.	Polysaccharides (Glycans)
8.	Lipids
9.	Carrageenan
10.	Bleomycin (Blenoxane)