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DNA-spermidine

used against radiation-induced leukopenia

Also Known As:

DA-51; spermidine-DNA

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 11752
  - DNA: 145982
    - DNA-spermidine: 7
Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - Spermidine: 1153
      - DNA-spermidine: 7
  - Biogenic Amines: 992
    - Biogenic Polyamines: 11
      - Putrescine: 919
        Spermidine: 1153
        DNA-spermidine: 7

Experts

1.	Qian, Hang: 3 articles (01/2022 - 05/2018)
2.	Wu, Di: 3 articles (01/2022 - 05/2018)
3.	He, Binfeng: 2 articles (01/2020 - 05/2018)
4.	Li, Jin: 2 articles (01/2020 - 05/2018)
5.	Liu, Qian: 2 articles (01/2020 - 05/2018)
6.	Mao, Chengde: 2 articles (01/2020 - 05/2018)
7.	Wang, Dong: 2 articles (01/2020 - 05/2018)
8.	Wang, Guansong: 2 articles (01/2020 - 05/2018)
9.	Chen, Huaping: 1 article (01/2022)
10.	Guo, Yuhang: 1 article (01/2022)

Related Diseases

1.	Leukopenia 01/25/1974 - "[Protective effect of DNA-spermidine (DA-51) against radiation-induced leukopenia. " 08/25/1976 - "[Protective effect of DNA-spermidine (DA-51) against radiation-induced leukopenia -a study on breast cancer patients receiving postoperative prophylactic irradiation (author's transl)]."
2.	Breast Neoplasms (Breast Cancer) 08/25/1976 - "[Protective effect of DNA-spermidine (DA-51) against radiation-induced leukopenia -a study on breast cancer patients receiving postoperative prophylactic irradiation (author's transl)]."
3.	Neoplasms (Cancer) 01/01/2020 - "Correction to Isothermal Self-Assembly of Spermidine-DNA Nanostructure Complex as a Functional Platform for Cancer Therapy." 05/09/2018 - "Isothermal Self-Assembly of Spermidine-DNA Nanostructure Complex as a Functional Platform for Cancer Therapy."
4.	Acute Lung Injury 01/01/2022 - "An mTOR siRNA-Loaded Spermidine/DNA Tetrahedron Nanoplatform with a Synergistic Anti-Inflammatory Effect on Acute Lung Injury."
5.	Glioma (Gliomas) 08/01/1997 - "The cellular uptake of the internally [32P]-radiolabeled hammerhead ribozyme in U87-MG glioma cells was temperature, energy, and pH dependent and involved an active process that could be competed with cold ribozyme of the same chemistry and sequence, an all 2'-O-methyl-modified ribozyme of the same sequence, antisense PS-ODNs, and a variety of other polyanions (salmon sperm DNA, spermidine, dextran sulfate, and heparin). "

Related Drugs and Biologics

1.	Small Interfering RNA (siRNA)
2.	Catalytic RNA (Ribozymes)
3.	Dextran Sulfate
4.	Cytokines
5.	Spermine
6.	Heparin (Liquaemin)
7.	Free Radicals
8.	Enzymes
9.	hammerhead ribozyme
10.	polyanions

Related Therapies and Procedures

1.	Therapeutics