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4,4'-dipyridyl disulfide

Also Known As:

4,4'-dipyridine disulfide; 4,4'-dithiodipyridine; 4,4'-dithiopyridine

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Hayashi, Hideki: 1 article (11/2016)
2.	Izumida, Mai: 1 article (11/2016)
3.	Kubo, Yoshinao: 1 article (11/2016)
4.	Matsuyama, Toshifumi: 1 article (11/2016)
5.	Tanaka, Yuetsu: 1 article (11/2016)
6.	Yashima, Yuka: 1 article (11/2016)
7.	Yasui, Kiyoshi: 1 article (11/2016)
8.	Yoshii-Kamiyama, Haruka: 1 article (11/2016)
9.	Chen, Wei-Chung: 1 article (11/2003)
10.	Ho, Chin-Man: 1 article (11/2003)

Related Diseases

1.	Osteosarcoma (Osteogenic Sarcoma) 11/01/2003 - "In this study, we show that 4,4'-dithiodipyridine (4,4'-DTDP), a reactive disulphide that mobilizes Ca(2+) in muscle, induces an increase in cytoplasmic free-Ca(2+) concentrations ([Ca(2+)](i)) in MG63 human osteosarcoma cells loaded with the Ca(2+)-sensitive dye fura-2. "
2.	Malignant Hyperthermia 12/01/1999 - "Time-dependent effects of cysteine modification were compared in skeletal ryanodine receptors (RyRs) from normal pigs and RyR(MH) (Arg(615) to Cys(615)) from pigs susceptible to malignant hyperthermia, using the oxidizing reagents 4,4'-dithiodipyridine (4, 4'-DTDP) and 5,5'-dithio-bis(2-nitrobenzoic acid) (DTNB) or the reducing agent dithiothreitol (DTT). "
3.	Ischemia 11/02/1998 - "Perfusion of control hearts with the sulfhydryl blocking agents 4,4'-dithiodipyridine (25 micromol/L) and N-ethylmaleimide (16 micromol/L) increased the resistance to ischemia and reduced sarcoplasmic reticulum Ca2+ release and [3H]-ryanodine binding. "
4.	Infections 11/01/2016 - "Finally, we found that 4,4'-dithiodipyridine (4-PDS), which inhibits S-S bond formation at acidic pH, significantly suppresses HIV-1 vector infection and virion production, like GILT. "

Related Drugs and Biologics

1.	Fura-2 (Fura 2)
2.	Coloring Agents (Dyes)
3.	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)
4.	Reducing Agents
5.	Ryanodine
6.	Indicators and Reagents (Reagents)
7.	Ethylmaleimide (N-Ethylmaleimide)
8.	Dithiothreitol (Cleland's Reagent)
9.	Dithionitrobenzoic Acid (Ellman's Reagent)
10.	Cysteine (L-Cysteine)