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4-dimethylaminostilbene

RN given refers to cpd without isomeric designation; structure

Also Known As:

4-dimethylaminostilbene, (cis)-isomer; 4-dimethylaminostilbene, (trans)-isomer; trans-4-dimethylaminostilbene

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        4-dimethylaminostilbene: 7

Related Diseases

1.	Carcinoma (Carcinomatosis) 11/01/1949 - "Histopathologic study of the mode of inhibition of cellular proliferation; effect of 4-dimethylaminostilbene on the growth of Walker rat carcinoma 256."
2.	Neoplasms (Cancer) 12/01/1981 - "Total binding of trans-4-dimethylaminostilbene metabolites to nucleic acids was highest in the liver, about one-fifth of that total amount in the kidney, less than one-fifth in the lung and glandular stomach (which is the target tissue for acute toxicity), and still less in the forestomach and Zymbal's gland, the tissue in which tumors arise after repeated administration of test compounds to female Wistar rats. " 08/01/1970 - "Skin tumors in ACI-N rats induced by 3-methylcholanthrene and 4-dimethylaminostilbene." 05/01/1965 - "II. Inhibitory effect of methylcholanthrene and 1,2-benzanthracene on tumor formation by 4-dimethylaminostilbene."
3.	Carcinogenesis 09/01/1962 - "II. Effect of pretreatment of painting with 20-methylcholanthrene or feeding of 4-dimethylaminostilbene upon carcinogenesis of 4-dimethylaminoazobenzene in the rat."
4.	Skin Neoplasms (Skin Cancer) 09/01/1962 - "III. Development of skin cancer in the rat by feeding 4-dimethylaminostilbene following initial painting of 20-methylcholanthrene."
5.	Liver Neoplasms (Liver Cancer) 09/01/1962 - "I. Development of liver cancer in the rat by the feeding of 4-dimethylaminostilbene following initial feeding of 4-dimethyiaminoazobenzene."

Related Drugs and Biologics

1.	Methylcholanthrene
2.	Nucleic Acids
3.	p-Dimethylaminoazobenzene (Methyl Yellow)
4.	benz(a)anthracene (benzanthracene)