17,20-dihydroxy-4-pregnen-3-one

a maturation-inducing hormone; possible role in regulation of testosterone synthesis by rat & rabbit testis; see also record for (20R)-isomer: 1662-06-2; RN given refers to all (alpha)-isomer; structure

Also Known As:

(20S)-isomer of 17,20-dihydroxy-4-pregnen-3-one; 17 alpha,20 alpha-dihydroxyprogesterone; 17,20 beta-dihydroxy-4-pregnen-3-one; 17,20beta-P; 17,20beta-dihydroxy-4-pregnen-3-one; 17a,20a-DHP; 17alpha,20beta-DP; 4-pregnene-17 alpha,20 alpha-diol-3-one; maturation-inducing steroid; 17 alpha,20 alpha-dihydroxy-4-pregnen-3-one

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced) 05/01/1987 - "[Studies on the significance of 17 alpha,20 alpha-dihydroxy-4-pregnen-3-one (17 alpha,20 alpha-P) in pregnancy induced hypertension (PIH) and its site of production]."
2.	Hypertension (High Blood Pressure) 03/20/1987 - "17 alpha, 20 alpha-dihydroxy-4-pregnen-3-one (17 alpha, 20 alpha-P) is reportedly a hyper-tensinogenic substance in a model of ACTH induced hypertension in sheep (Scoggins et al). "
3.	Herpes Zoster 04/01/1991 - "The SDS PAGE of the cytosol and zona radiata PA labelled protein gave very similar subunits indicating that the membrane protein and the cytosol protein, both of which bind the maturation inducing steroid (MIS) 17α,20β-dihydroxy-4-pregnen-3-one (17α,20β-DHP), have similar subunit structures. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Membrane Proteins (Integral Membrane Proteins)
3.	Adrenocorticotropic Hormone (ACTH)