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4-cymene (p-cymene)

structure
Also Known As:
p-cymene; p-cymol; p-isopropyltoluene
Networked: 36 relevant articles (3 outcomes, 5 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Sadler, Peter J: 6 articles (07/2015 - 01/2010)
2. Dyson, Paul J: 5 articles (04/2015 - 09/2008)
3. Jakupec, Michael A: 5 articles (07/2013 - 05/2009)
4. Keppler, Bernhard K: 5 articles (07/2013 - 05/2009)
5. Arion, Vladimir B: 5 articles (07/2013 - 05/2009)
6. Fu, Ying: 3 articles (07/2015 - 11/2010)
7. Romero-Canelón, Isolda: 3 articles (07/2015 - 02/2013)
8. Pizarro, Ana M: 3 articles (07/2015 - 01/2010)
9. van Rijt, Sabine H: 3 articles (05/2014 - 01/2010)
10. Hartinger, Christian G: 3 articles (07/2013 - 09/2008)

Related Diseases

1. Acute Lung Injury
2. Infection
3. Breast Neoplasms (Breast Cancer)
4. Neoplasms (Cancer)
05/21/2013 - "Our results consistently indicate that [Ru2(p-cymene)2(L4)2]Cl2 is quite promising as a prospective metallodrug for cancer chemotherapy."
12/01/2014 - "In this study, a series of arene ruthenium complexes, [(η6-arene)Ru(H2iip)Cl]Cl (arene = p-cymene, RAWQ03; CH3C6H5, RAWQ04; and C6H6, RAWQ11), were synthesized and their inhibitory activity against tumor cells were evaluated. "
04/23/2015 - "Following the identification of [Ru(η(6)-p-cymene)Cl2(1H,1H,2H,2H-perfluorodecyl-3-(pyridin-3-yl)propanoate)], a ruthenium(II)-arene complex with a perfluoroalkyl-modified ligand that displays remarkable in vitro cancer cell selectivity, a series of structurally related compounds were designed. "
02/14/2013 - "Organometallic half-sandwich complexes [M(p-cymene)(azo/imino-pyridine)X](+) where M = Ru(II) or Os(II) and X ═ Cl or I, exhibit potent antiproliferative activity toward a range of cancer cells. "
11/01/2012 - "Complexes with the general formula [M(II)Cl(η(6)-p-cymene)L]Cl, where M=Ru (1, 3) or Os (2, 4), and L=L(1) (1, 2) or L(2) (3, 4), L(1)=N-(9-bromo-7,12-dihydroindolo[3,2-d][1]-benzazepin-6(5H)-yliden-N'-(2-hydroxybenzylidene)azine and L(2)=N-(9-bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6-yl)-N'-[3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl-methylene]azinium chloride (L(2)(*)HCl), were now investigated regarding cytotoxicity and accumulation in cancer cells, impact on the cell cycle, capacity of inhibiting DNA synthesis and inducing apoptosis as well as their ability to inhibit Cdk activity. "
5. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)

Related Drugs and Biologics

1. Thymol
2. linalyl acetate
3. caprylic acid (octanoate)
4. Cisplatin (Platino)
5. Cytokines
6. Peroxidase (Myeloperoxidase)
7. Ruthenium
8. Osmium
9. diphenyl (biphenyl)
10. Ligands

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)