conessine

Also Known As:

(3-beta)-N,N-dimethyl-on-5-enin-3-amine dihydrobromide; (3-beta)-N,N-dimethylcon-5-enin-3-amine; 3 beta-(dimethylamino)con-5-enine; 3-beta-(dimethylamino)con-5-enine dihydrobromide; conessine HBr; conessine dihydrobromide; conessine dihydrobromide, (3beta)-isomer; conessine hydrobromide

Networked: 26 relevant articles (4 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - conessine: 26

Experts

1.	Choe, Joonho: 2 articles (04/2018 - 02/2018)
2.	Choi, Inho: 2 articles (04/2018 - 02/2018)
3.	Jang, Minsu: 2 articles (04/2018 - 02/2018)
4.	Jo, Daum: 2 articles (04/2018 - 02/2018)
5.	Kim, Hyunju: 2 articles (04/2018 - 02/2018)
6.	Oh, Won Keun: 2 articles (04/2018 - 02/2018)
7.	Park, Junsoo: 2 articles (04/2018 - 02/2018)
8.	Park, Rackhyun: 2 articles (04/2018 - 02/2018)
9.	Arif, Muhammad: 1 article (02/2020)
10.	Boren, Jan: 1 article (02/2020)

Related Diseases

1.	Muscular Atrophy (Muscle Atrophy) 04/28/2018 - "These results collectively suggest that conessine is potentially useful in the treatment of muscle atrophy." 02/01/2018 - "These results collectively suggest that conessine is potentially useful in the treatment of muscle atrophy." 04/28/2018 - "Finally, we demonstrated that conessine treatment reduced dexamethasone-induced muscle atrophy using differentiated C2C12 cells. " 04/28/2018 - "Conessine Treatment Reduces Dexamethasone-Induced Muscle Atrophy by Regulating MuRF1 and Atrogin-1 Expression." 02/01/2018 - "Finally, we demonstrated that conessine treatment reduced dexamethasone-induced muscle atrophy using differentiated C2C12 cells. "
2.	Infections 10/19/2018 - "This study aimed to evaluate the efficacy of combinations of steroidal alkaloids and conessine from the Thai medicinal plant Holarrhena antidysenterica with antibiotics against Pseudomonas aeruginosa strains possessing different efflux-pump-mediated multidrug-resistant (MDR) phenotypes in a Galleria mellonella infection model. " 10/19/2018 - "Efficacy of combinations of the steroidal alkaloids and conessine with levofloxacin were compared with monotherapies against infections in G. "
3.	Communicable Diseases (Infectious Diseases) 12/01/2023 - "Our work suggests that conessine could be developed as a prophylactic and therapeutic treatment for infectious diseases caused by enveloped viruses." 02/16/2007 - "These results support common use of stem bark of Hf and conessine isolated from Hf in the treatment of some infectious diseases."
4.	Amebic Dysentery (Amoebic Dysentery) 09/15/1949 - "Trials for the treatment of acute intestinal amebiasis in Indochina by conessine and by total extracts of Holarrhena floribunda; therapeutic incidents." 01/01/1948 - "Research on the therapeutic properties of conessine; new trials to treat amoebic dysentery with conessine hydrochloride." 04/01/1950 - "II. Elimination of conessine in man during treatment of amebic dysentery]." 10/15/1949 - "Conessine in the treatment of childhood amoebic dysentery." 10/15/1949 - "New observations on the treatment of amoebic dysentery with conessine."
5.	Malaria 01/01/1948 - "Research on the therapeutic properties of conessine, preliminary trials in the treatment of malaria and intestinal amebiasis; will emin be ruled by the conessine?" 06/10/2013 - "The present study shows evaluation of anti-malarial effects of compound conessine isolated from plant Holarrhena antidysenterica frequently used against malaria in the Garhwal region of north-west Himalaya. "

Related Drugs and Biologics

1.	Alkaloids
2.	Anti-Bacterial Agents (Antibiotics)
3.	Levofloxacin (Levaquin)
4.	Antiviral Agents (Antivirals)
5.	Antimalarials (Antimalarial Agents)
6.	Ubiquitin
7.	Ligases (Synthetase)
8.	Dexamethasone (Maxidex)
9.	Nizatidine (Axid)
10.	Fenoterol

Related Therapies and Procedures

1.	Therapeutics