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cinnamyl anthranilate
Also Known As:
3-phenyl-2-propenyl-2-aminobenzoate
Networked:
5
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzoates: 426
Aminobenzoates: 1
ortho-Aminobenzoates: 8
cinnamyl anthranilate: 5
Carboxylic Acids: 973
Carbocyclic Acids
Benzoates: 426
Aminobenzoates: 1
ortho-Aminobenzoates: 8
cinnamyl anthranilate: 5
Related Diseases
1.
Carcinogenesis
03/01/1981 - "
Report on carcinogenesis bioassay of cinnamyl anthranilate.
"
09/01/1994 - "
Results from these concurrent FCM and ARG investigations include the following: (1) conclusions (DNA repair positive or negative) were in agreement, with one exception, cinnamyl anthranilate, for which cytotoxic doses produced a positive FCM response, but lack of intact hepatocytes in parallel ARG preparations prevented analysis; (2) similar sensitivities for most of the positive chemicals were reported; (3) a high correlation (85%) exists between the reported genotoxicity classification and these DNA repair results in the absence of overt cytotoxicity; (4) a poor correlation exists between these DNA repair results and hepatocarcinogenesis (only 4/11 liver carcinogens tested positive) or overall carcinogenesis in the male rat (only 9/21 carcinogens tested positive).
"
2.
Body Weight (Weight, Body)
03/01/1996 - "
Dietary administration to male and female B6C3F1 mice for 21 days over a dose range of 0 to 30,000 ppm revealed the same qualitative picture with no intact cinnamyl anthranilate detected in urine at or below 1000 ppm (equivalent to 100 mg/kg body weight).
"
06/01/1985 - "
Following a single oral dose of 500 mg cinnamyl anthranilate/kg body weight to B6C3F1 mice peak plasma levels of unchanged compound were reached in 30 min, and were higher in males than in females.
"
3.
Hypertrophy
06/01/1985 - "
It is important to note that liver hypertrophy, microsomal enzyme induction and the excretion of unchanged cinnamyl anthranilate all have the same dose-threshold for their appearance.
"
4.
Hepatocellular Carcinoma (Hepatoma)
08/01/1980 - "
It was concluded that under the conditions of this bioassay cinnamyl anthranilate was carcinogenic for male and female B6C3F1 mice, inducing increased incidences of hepatocellular carcinomas or adenomas.
"
5.
Adenoma (Adenomas)
08/01/1980 - "
It was concluded that under the conditions of this bioassay cinnamyl anthranilate was carcinogenic for male and female B6C3F1 mice, inducing increased incidences of hepatocellular carcinomas or adenomas.
"
Related Drugs and Biologics
1.
Carcinogens