|1.||Seneff, Stephanie: 2 articles (01/2015 - 02/2012)|
|2.||Elias, Peter M: 2 articles (03/2014 - 04/2008)|
|3.||Williams, Mary L: 2 articles (03/2014 - 04/2008)|
|4.||Iwamori, Masao: 2 articles (09/2012 - 08/2006)|
|5.||Cooks, R Graham: 2 articles (05/2012 - 05/2010)|
|6.||Eberlin, Livia S: 2 articles (05/2012 - 05/2010)|
|7.||Zhai, Yonggong: 1 article (03/2015)|
|8.||Li, Jiao: 1 article (03/2015)|
|9.||Cong, Yusheng: 1 article (03/2015)|
|10.||Wang, Jing: 1 article (03/2015)|
|1.||X-Linked Ichthyosis (Ichthyosis, X Linked)
07/01/1981 - "Eight subjects (age 3 months-74 years) with steroid sulfatase deficiency had strikingly elevated cholesterol sulfate levels with means and ranges as follows: plasma - 3,300 micrograms/100 ml (2,700-4,000), red cell membranes- 7,500 (5,200-9,800) Cholesterol sulfate is known to effect membrane stability and the present observations may help to explain the pathogenesis of STS deficiency and x-linked ichthyosis."
03/01/2014 - "Role of cholesterol sulfate in epidermal structure and function: lessons from X-linked ichthyosis."
04/01/2008 - "For example, in recessive X-linked ichthyosis (RXLI), cholesterol sulfate (CSO(4)) accumulation also produces a permeability barrier defect through lamellar/nonlamellar phase separation. "
04/01/2007 - "STS deficiency in X-linked ichthyosis leads to cholesterol sulfate accumulation, which induces transglutaminase-1 dysfunction. "
11/01/1998 - "[X-linked ichthyosis: development of a new cellular and metabolic model of cholesterol sulfate]."
07/01/2014 - "infection leads to increased presence of cholesteryl sulfate in this tissue. "
04/01/1989 - "Amphotericin B-deoxycholate given iv at a dose of 1.5 mg/kg was more effective in sterilizing liver and kidney than the amphotericin/cholesterol-sulfate complexes given iv at 1.5-4.5 mg/kg, but infection persisted in the lungs of all rabbits treated with those doses. "
04/01/1989 - "Infection persisted even when the rabbits were given a lethal dose of amphotericin B-deoxycholate (4.5 mg/kg), but a dose of 15 mg/kg of the amphotericin/cholesterol-sulfate complexes sterilized tissues and was associated with no acute lethality. "
03/01/1993 - "Subsequent chemotherapy given for relapse of the leukemia was followed by a new fungal infection, which was treated with AmB-cholesteryl sulfate complex (Amphocil).(ABSTRACT TRUNCATED AT 250 WORDS)"
04/01/1989 - "The amphotericin/cholesterol-sulfate complexes appear to be an improved means of amphotericin B delivery and may improve therapy for invasive aspergillosis."
01/01/1998 - "In November 1996, amphotericin B cholesteryl sulfate complex for injection (Amphotec, Sequus Pharmaceuticals, Menlo Park, CA), a second preparation composed of a disc-like structure, received FDA approval for the treatment of invasive aspergillosis in patients in whom renal impairment or unacceptable toxicity precludes the use of conventional AmB therapy and in patients in whom prior AmB therapy has failed. "
04/01/1989 - "An immunosuppressed rabbit model of invasive aspergillosis was used to evaluate a novel micellar preparation of cholesterol sulfate complexed to amphotericin B. "
04/01/1989 - "Treatment of experimental invasive aspergillosis with novel amphotericin B/cholesterol-sulfate complexes."
|4.||Leprosy (Hansen's Disease)
11/01/1995 - "Cholesterol sulfate, when applied topically at a dose of 400 micrograms (820 mumol) 10 min before treatment with the promoters, markedly suppressed tumor formation, resulting in decrease of 56% in the incidence of tumor-bearing mice, 81% in the number of tumors/mouse, and 60% in the size of tumors at 20 weeks of the promotion. "
01/01/1967 - "Isolation of cholesterol sulfate from human aortas and adrenal tumors."
11/01/1995 - "These findings suggest that cholesterol sulfate inhibits tumor promotion by stimulating a differentiation pathway mediated by the eta isoform of protein kinase C."
11/01/1995 - "Cholesterol sulfate, unlike most inhibitors of tumor promotion, did not inhibit induction of ornithine decarboxylase and hyperplasia in mouse epidermis caused by topical treatment with 12-O-tetradecanoylphorbol-13-acetate. "
04/07/2006 - "Taken together, it is likely that binding of matrilysin to cholesterol sulfate facilitates the matrilysin-catalyzed modulation of cell surface proteins, thus inducing the cancer cell aggregation."
|1.||Amphotericin B (Amphotericin)
|2.||deoxycholate drug combination amphotericin B
|3.||Steryl-Sulfatase (Steroid Sulfatase)
|8.||Cholesterol Esters (Cholesteryl Esters)
|10.||Nonesterified Fatty Acids (NEFA)
|1.||Drug Therapy (Chemotherapy)