butylurea

01/01/2005 - "Butylurea, the lead compound is also effective against other sexually transmitted diseases (STDs) while sparing the normal vaginal flora. "

06/01/1978 - "Cytogenetic studies were done on 34 primary leukemias induced by N-nitroso-N-butylurea (NBU) in outbred Long-Evans rats. "
02/27/1998 - "ras and p53 genes are infrequently involved in N-nitroso-N-butylurea (NBU)-induced rat leukemia."
06/01/1978 - "Involvement of chromosome No. 2 in chromosome changes in primary leukemia induced in rats by N-nitroso-N-butylurea."
02/27/1998 - "In this study, we present N-nitroso-N-butylurea (NBU)-induced rat leukemia and compare it with the genetic alterations found in 7,12-dimethylbenz[a]anthracene (DMBA)-induced erythroblastic leukemias which consistently have an A to T transversion at the second base of codon 61 in N-ras. "

01/01/1976 - "The anti-pentetrazole activity of tert-butylurea suggests its possible effectiveness against 'petit mal' seizures and, therefore, calls for additional studies to evaluate the anticonvulsant activity of tert-butylurea."

01/01/1981 - "No tumors was seen with nitrosoallylurea, nitroso-iso-butylurea, nitrosobenzylurea, and nitroso-2-phenylethylurea. "
08/01/1975 - "N-Nitroso-N-butylurea also induced tumors of the stomach, hematopoietic system, lung, and liver."
08/01/1975 - "Intestinal tumors occurred in 100% of the mice that survived more than 15 weeks after injection with a high dose of N-nitroso-N-butylurea at 6 weeks of age, and in 35 to 70% of the mice in other treatment groups. "
08/01/1975 - "Intestinal tumors in mice treated with a single injection of N-nitroso-N-butylurea."
02/01/1979 - "The number and type of neoplasms were not significantly increased in either species receiving butylurea or sodium nitrite only. "

02/01/1980 - "Membrane markers expressed by a transplantable granulocytic leukemia induced in inbred strain 13 guinea pigs by N-nitroso-N-butylurea have been investigated by serologic and immunochemical methods. "
10/01/1978 - "Analysis of synthetic RNA-directed DNA polymerase activities in the spleen of a rat with myelogenous leukemia induced by N-nitroso-N-butylurea."
01/01/1978 - "The occurrence of a granulocytic leukemia in 1 of 40 female strain 13/N guinea pigs given N-nitroso-N-butylurea continuously in their drinking water for 21 weeks is reported here. "