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aprofen

RN given refers to parent cpd; structure

Also Known As:

2,2-diphenylpropanoic acid N,N-diethylaminoethyl ester; aprofen hydrochloride; aprophen; 2-diethylaminoethyl 2,2-diphenylpropionate

Networked: 8 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phenylpropionates
      - aprofen: 8

Experts

1.	Alcalay, M: 1 article (12/2001)
2.	Alkalay, D: 1 article (12/2001)
3.	Cohen, G: 1 article (12/2001)
4.	Givoni, S: 1 article (12/2001)
5.	Grauer, E: 1 article (12/2001)
6.	Kapon, J: 1 article (12/2001)
7.	Liani, H: 1 article (12/2001)
8.	Raveh, L: 1 article (12/2001)
9.	Tashma, Z: 1 article (12/2001)
10.	Copeland, T L: 1 article (01/2000)

Related Diseases

1.	Poisoning 12/01/2001 - "At the anticonvulsive doses (125-250 microg x kg(-1), i.p.) bretazenil, in combination with pyridostigmine (100 microg x kg(-1), i.m.) and aprophen (4 mg x kg(-1), i.m.), conferred prophylactic protection against sarin and soman poisoning (protective ratios 2.6 and 2.1, respectively). "
2.	Organophosphate Poisoning 07/01/1989 - "Binary antidotes for organophosphate poisoning: aprophen analogues that are both antimuscarinics and carbamates." 11/01/1987 - "Certain muscarinic antagonists (e.g., atropine, aprophen, and benactyzine) are used as antidotes for the treatment of organophosphate poisoning. " 07/01/1989 - "Prophylaxis against organophosphate poisoning can be achieved by pretreatment with physostigmine or pyridostigmine, which are carbamates, and aprophen, which is an anticholinergic agent. "
3.	Peptic Ulcer (Peptic Ulcers) 03/01/1962 - "[Treatment of patients with peptic ulcer with aprophen]." 06/01/1963 - "[DYNAMICS OF THE FUNCTIONAL STATE OF THE STOMACH IN PATIENTS WITH CHRONIC GASTRITIS AND PEPTIC ULCER UNDER THE INFLUENCE OF APROPHEN]."
4.	Seizures (Absence Seizure) 01/01/2000 - "With the exception of atropine, all anticholinergic drugs were effective at lower doses than diazepam in terminating seizures when given 5 min after seizure onset; benactyzine, procyclidine and aprophen terminated seizures most rapidly while scopolamine, trihexyphenidyl, biperiden, and diazepam were significantly slower. "
5.	Prolonged Pregnancy 01/01/1990 - "In 51 chronological prolonged pregnancies at 42 weeks gestation the preparation and induction was made usage of the Soviet spasmolytic preparation Aprophen. " 01/01/1990 - "[Delivery in prolonged pregnancy following preparation and induction with aprofen and prednisolone]."

Related Drugs and Biologics

1.	Pyridostigmine Bromide (Pyridostigmine)
2.	Soman
3.	Sarin
4.	bretazenil
5.	Muscarinic Antagonists
6.	Cholinergic Antagonists (Anticholinergics)
7.	Benactyzine
8.	Atropine
9.	Trihexyphenidyl (Artane)
10.	Scopolamine (Hyoscine)