HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

apoceruloplasmin

ceruloplasmin deficient in copper

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ilyicheva, E Yu: 1 article (03/2018)
2.	Karpenko, M N: 1 article (03/2018)
3.	Milyukhina, I V: 1 article (03/2018)
4.	Muruzheva, Z M: 1 article (03/2018)
5.	Orlov, Yu A: 1 article (03/2018)
6.	Puchkova, L V: 1 article (03/2018)
7.	Chen, Chen: 1 article (07/2015)
8.	Duff Canning, Sarah Jane: 1 article (07/2015)
9.	Shen, Bo: 1 article (07/2015)
10.	Wang, Xiao-Ping: 1 article (07/2015)

Related Diseases

1.	Hepatolenticular Degeneration (Wilson's Disease) 12/01/2004 - "ATP7B is the gene product of the Wilson disease gene located on chromosome 13 and resides in hepatocytes in the trans-Golgi network, transporting copper into the secretory pathway for incorporation into apoceruloplasmin and excretion into the bile. " 08/20/1999 - "Significantly, the developmental expression pattern of sCP was closely correlated with that of the sheep Wilson disease gene (sATP7B), suggesting that the expression of the two genes may be coordinated to ensure that copper is supplied to apoceruloplasmin. " 10/01/1974 - "Determination of apoceruloplasmin by radioimmunoassay in nutritional copper deficiency, Menkes' kinky hair syndrome, Wilson's disease, and umbilical cord blood." 12/01/2010 - "Wilson's disease is a rare autosomal recessive disorder of copper transport due to mutations in the ATP7B gene, responsible for transport of copper into bile from hepatocytes and its incorporation into apoceruloplasmin to form ceruloplasmin resulting in excessive accumulation of copper in the liver and extrahepatic tissues. "
2.	Whooping Cough (Pertussis) 01/01/1991 - "Further evaluation of the pertussis component vaccine produced by apoceruloplasmin affinity chromatography."
3.	Vitamin A Deficiency 01/01/1979 - "In these conditions serum and liver levels of vitamin A are normal and do not vary, ceruloplasmin level is zero; however apoceruloplasmin is still being synthetized : Nevertheless at the ultime state of the deficiency vitamin A level decreases while apoceruloplasmin increases. "
4.	Retinal Degeneration 05/01/1987 - "Ceruloplasmin is involved in iron metabolism, and the findings suggest that hypoceruloplasminemia due to lack of apoceruloplasmin was causally linked to the iron deposition in basal ganglia and other organs, leading to blepharospasm and retinal degeneration."
5.	Parkinson Disease (Parkinson's Disease) 03/01/2018 - "Serum concentration of copper, immunoreactive polypeptides of ceruloplasmin and its oxidase activity, and the number of copper atoms per ceruloplasmin molecule were decreased in patients with Parkinson's disease in comparison with the corresponding parameters in age-matched healthy individuals, but the ratio of apoceruloplasmin to holoceruloplasmin in patients with Parkinson's disease was similar in both groups. "

Related Drugs and Biologics

1.	Copper
2.	Ceruloplasmin (Ferroxidase)
3.	Vitamin A (Retinol)
4.	Vaccines
5.	Proteins (Proteins, Gene)
6.	Peptides (Polypeptides)
7.	Oxidoreductases (Dehydrogenase)
8.	Iron
9.	Familial apoceruloplasmin deficiency