|1.||Yanagita, Ryo C: 6 articles (01/2015 - 06/2009)|
|2.||Irie, Kazuhiro: 6 articles (01/2015 - 06/2009)|
|3.||Nakagawa, Yu: 4 articles (05/2012 - 06/2009)|
|4.||Tokuda, Harukuni: 3 articles (01/2015 - 10/2010)|
|5.||Murakami, Akira: 3 articles (01/2011 - 06/2009)|
|6.||Nagai, Hiroshi: 3 articles (01/2011 - 06/2009)|
|7.||Aida, Misako: 1 article (01/2015)|
|8.||Hanaki, Yusuke: 1 article (01/2015)|
|9.||Sugahara, Takahiro: 1 article (01/2015)|
|10.||Suzuki, Nobutaka: 1 article (01/2015)|
01/01/2015 - "Aplog-1 is a simplified analog of the tumor-promoting aplysiatoxin with anti-proliferative and cytotoxic activities against several cancer cell lines. "
04/01/2014 - "We have recently identified 10-methyl-aplog-1 (26), a simplified analog of tumor-promoting aplysiatoxin (ATX), as a possible therapeutic lead for cancer. "
05/01/2012 - "The authors focused on the bryo-1's unique mechanism of activating PKCδ that plays a tumor suppressor role, and found that a simple and less lipophilic analogue (aplog-1) of the tumor-promoting aplysiatoxin showed PKCδ-activating behavior similar to bryo-1. "
01/01/2011 - "Synthesis and biological evaluation of the 12,12-dimethyl derivative of Aplog-1, an anti-proliferative analog of tumor-promoting aplysiatoxin."
06/10/2009 - "We report here easy access (22 steps) to a simple analogue (1) of the tumor-promoting aplysiatoxin (ATX) as a novel PKC activator with anticancer and anti-tumor-promoting activities. "
05/01/2002 - "The cause of death and the effective dose levels resembled those of aplysiatoxin poisoning."
01/01/2000 - "The cause of death by aplysiatoxin poisoning was bleeding from the small intestine in mice. "
01/01/2000 - "Bleeding from the small intestine caused by aplysiatoxin, the causative agent of the red alga Gracilaria coronopifolia poisoning."
12/01/1998 - "Morphological observations of diarrhea in mice caused by aplysiatoxin, the causative agent of the red alga Gracilaria coronopifolia poisoning in Hawaii."
07/01/1996 - "The human symptoms and the amount of these toxins in the original algal samples indicate that aplysiatoxin and debromoaplysiatoxin were the causative agents of the human poisoning incidents. "
|3.||Protein Kinase C
|7.||Arachidonic Acid (Vitamin F)
|9.||Protein Kinases (Protein Kinase)