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aminorex fumarate

RN given refers to fumarate[1:1]
Also Known As:
aminorex fumarate, fumarate (2:1)
Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1. Pulmonary Arterial Hypertension
2. Pulmonary Hypertension
3. Familial Primary Pulmonary Hypertension
04/01/1998 - "In the late 1960s, an epidemic of primary pulmonary hypertension (PPH) occurred in Europe shortly after the introduction of aminorex fumarate, a potent anorexigen. "
10/01/1999 - "Primary pulmonary hypertension (PPH) in association with weight loss treatment was initially observed in the late 1960s and early 1970s with the diet pill aminorex fumarate. "
07/01/1990 - "Although an exact etiopathogenetic differentiation was not possible, three groups of patients were identified clinically: patients with so-called primary pulmonary hypertension (PPH)--group 1; patients with pulmonary hypertension induced by anorexipens (aminorex fumarate)--group 2; and patients with pulmonary hypertension due to emboli in the large pulmonary vessels--group 3. In addition to non-invasive echocardiographic assessment of pulmonary pressures, regular cardiac catheterizations were carried out, which revealed right atrial mean pressure, cardiac output, and mixed venous saturation to be prognostic predictive factors. "
04/01/1986 - "Selected cases of severe primary pulmonary arterial hypertension and associated pulmonary vascular disease have been related to the oral ingestion of aminorex fumarate, an anorexigen obviously responsible for an epidemic of primary pulmonary hypertension in Western Europe between 1967 and 1970. "
12/01/1998 - "Anorexigens such as aminorex fumarate and dexfenfluramine are associated with the development of severe pulmonary hypertension (PH), which clinically and histopathologically is considered indistinguishable from idiopathic or primary pulmonary hypertension (PPH). "
4. Weight Loss (Weight Reduction)
5. Vascular Diseases (Vascular Disease)

Related Drugs and Biologics

1. Appetite Depressants (Anorectics)
2. Aminorex
3. Dexfenfluramine (Redux)
4. Mephenytoin (Mesantoin)
5. Debrisoquin (Debrisoquine)