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aminorex fumarate
RN given refers to fumarate[1:1]
Also Known As:
aminorex fumarate, fumarate (2:1)
Networked:
10
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Oxazoles: 89
Aminorex: 55
aminorex fumarate: 10
Related Diseases
1.
Pulmonary Arterial Hypertension
04/04/1970 - "
Aminorex fumarate: a double-blind trial and examination for signs of pulmonary arterial hypertension.
"
04/01/1986 - "
Selected cases of severe primary pulmonary arterial hypertension and associated pulmonary vascular disease have been related to the oral ingestion of aminorex fumarate, an anorexigen obviously responsible for an epidemic of primary pulmonary hypertension in Western Europe between 1967 and 1970.
"
2.
Pulmonary Hypertension
07/01/1990 - "
Although an exact etiopathogenetic differentiation was not possible, three groups of patients were identified clinically: patients with so-called primary pulmonary hypertension (PPH)--group 1; patients with pulmonary hypertension induced by anorexipens (aminorex fumarate)--group 2; and patients with pulmonary hypertension due to emboli in the large pulmonary vessels--group 3. In addition to non-invasive echocardiographic assessment of pulmonary pressures, regular cardiac catheterizations were carried out, which revealed right atrial mean pressure, cardiac output, and mixed venous saturation to be prognostic predictive factors.
"
04/01/1986 - "
This report describes a fifteen year follow-up of a female patient with aminorex fumarate related pulmonary hypertension and the uncommon finding of the formation of an excessive fusiform pulmonary trunk aneurysm in the late stage of the disease process.
"
11/01/1996 - "
The appetite suppressant aminorex fumarate is thought to have caused an epidemic of pulmonary hypertension in Europe in the 1960s.
"
07/01/1990 - "
Owing to the temporally limited effect of the pulmonary hypertension-inducing agent, aminorex fumarate (Menocil), patients with anorexigen-induced pulmonary hypertension may be considered a model group for drug-induced vascular pathology.
"
12/15/1973 - "
[Evolution of primary vascular pulmonary hypertension following ingestion of aminorex fumarate (Menocil).
"
3.
Familial Primary Pulmonary Hypertension
04/01/1998 - "
In the late 1960s, an epidemic of primary pulmonary hypertension (PPH) occurred in Europe shortly after the introduction of aminorex fumarate, a potent anorexigen.
"
10/01/1999 - "
Primary pulmonary hypertension (PPH) in association with weight loss treatment was initially observed in the late 1960s and early 1970s with the diet pill aminorex fumarate.
"
07/01/1990 - "
Although an exact etiopathogenetic differentiation was not possible, three groups of patients were identified clinically: patients with so-called primary pulmonary hypertension (PPH)--group 1; patients with pulmonary hypertension induced by anorexipens (aminorex fumarate)--group 2; and patients with pulmonary hypertension due to emboli in the large pulmonary vessels--group 3. In addition to non-invasive echocardiographic assessment of pulmonary pressures, regular cardiac catheterizations were carried out, which revealed right atrial mean pressure, cardiac output, and mixed venous saturation to be prognostic predictive factors.
"
04/01/1986 - "
Selected cases of severe primary pulmonary arterial hypertension and associated pulmonary vascular disease have been related to the oral ingestion of aminorex fumarate, an anorexigen obviously responsible for an epidemic of primary pulmonary hypertension in Western Europe between 1967 and 1970.
"
12/01/1998 - "
Anorexigens such as aminorex fumarate and dexfenfluramine are associated with the development of severe pulmonary hypertension (PH), which clinically and histopathologically is considered indistinguishable from idiopathic or primary pulmonary hypertension (PPH).
"
4.
Weight Loss (Weight Reduction)
10/01/1999 - "
Primary pulmonary hypertension (PPH) in association with weight loss treatment was initially observed in the late 1960s and early 1970s with the diet pill aminorex fumarate.
"
5.
Vascular Diseases (Vascular Disease)
04/01/1986 - "
Selected cases of severe primary pulmonary arterial hypertension and associated pulmonary vascular disease have been related to the oral ingestion of aminorex fumarate, an anorexigen obviously responsible for an epidemic of primary pulmonary hypertension in Western Europe between 1967 and 1970.
"
Related Drugs and Biologics
1.
Appetite Depressants (Anorectics)
2.
Aminorex
3.
Dexfenfluramine (Redux)
4.
Mephenytoin (Mesantoin)
5.
Debrisoquin (Debrisoquine)