aminorex fumarate

RN given refers to fumarate[1:1]
Also Known As:
aminorex fumarate, fumarate (2:1)
Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1. Pulmonary Hypertension (Ayerza Syndrome)
11/01/1996 - "The appetite suppressant aminorex fumarate is thought to have caused an epidemic of pulmonary hypertension in Europe in the 1960s. "
01/30/1971 - "Of 40 patients with obstructive pulmonary hypertension studied in Basle, Switzerland, during the period 1966-68, 32 had been taking an anorectic drug, aminorex fumarate. "
04/01/1986 - "This report describes a fifteen year follow-up of a female patient with aminorex fumarate related pulmonary hypertension and the uncommon finding of the formation of an excessive fusiform pulmonary trunk aneurysm in the late stage of the disease process. "
07/01/1990 - "Owing to the temporally limited effect of the pulmonary hypertension-inducing agent, aminorex fumarate (Menocil), patients with anorexigen-induced pulmonary hypertension may be considered a model group for drug-induced vascular pathology."
07/01/1990 - "Although an exact etiopathogenetic differentiation was not possible, three groups of patients were identified clinically: patients with so-called primary pulmonary hypertension (PPH)--group 1; patients with pulmonary hypertension induced by anorexipens (aminorex fumarate)--group 2; and patients with pulmonary hypertension due to emboli in the large pulmonary vessels--group 3. In addition to non-invasive echocardiographic assessment of pulmonary pressures, regular cardiac catheterizations were carried out, which revealed right atrial mean pressure, cardiac output, and mixed venous saturation to be prognostic predictive factors. "
2. Weight Loss (Weight Reduction)
3. Vascular Diseases (Vascular Disease)
4. Aneurysm (Aneurysms)

Related Drugs and Biologics

1. Idiopathic pulmonary hypertension
2. Aminorex
3. Dexfenfluramine (Redux)
4. Mephenytoin (Mesantoin)
5. Debrisoquin (Debrisoquine)