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4-aminobenzyl alcohol

structure

Also Known As:

p-aminobenzyl alcohol

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        Benzyl Alcohols: 7
        4-aminobenzyl alcohol: 3
- Alcohols: 595
  - Benzyl Alcohols: 7
    - 4-aminobenzyl alcohol: 3

Experts

1.	Chowdhury, Morshed A: 1 article (11/2019)
2.	Mousseau, Darrell D: 1 article (11/2019)
3.	Nyarko, Jennifer N K: 1 article (11/2019)
4.	Phenix, Christopher P: 1 article (11/2019)
5.	Vigliarolo, Brady G: 1 article (11/2019)
6.	Wang, Shusheng: 1 article (11/2019)
7.	Chen, Hong-Yuan: 1 article (12/2016)
8.	Feng, Liandong: 1 article (12/2016)
9.	Li, Jinbo: 1 article (12/2016)
10.	Wang, Yuqi: 1 article (12/2016)

Related Diseases

1.	Neoplasms (Cancer) 11/01/2019 - "Enzyme activity assays using a recombinant human enzyme and cancer cell lysates coupled with confocal microscopy experiments demonstrated that one of the probes, derivatized with the self-immolative prodrug linker p-aminobenzyl alcohol, can selectively report on Cathepsin B in biological samples including live cells." 12/20/2016 - "Herein, we reported a lysosome-targeting fluorogenic small-molecule probe for fluorescence imaging of lysosomal CTB in living cancer cells by incorporating a CTB-recognitive peptide substrate Cbz-Lys-Lys-p-aminobenzyl alcohol (Cbz-Lys-Lys-PABA) and a lysosome locating group morpholine. "
2.	Liver Neoplasms (Liver Cancer) 11/30/2006 - "More complex structures with a p-aminobenzyl alcohol (PABA) self-eliminating spacer showed better growth inhibition (IC50=50 nM for Hep G2 liver cancer cells) while exhibiting reduced toxicity toward rat cardiomyocytes, relative to the parent drug doxorubicin. "

Related Drugs and Biologics

1.	4-Aminobenzoic Acid (4 Aminobenzoic Acid)
2.	Prodrugs
3.	Peptides (Polypeptides)
4.	Enzymes
5.	Doxorubicin (Adriamycin)
6.	Cathepsin B
7.	morpholine
8.	lysyllysine (Lys-Lys)