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amfonelic acid
CNS-stimulant
Also Known As:
7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
Networked:
5
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Quinolines: 146
Quinolones: 2938
4-Quinolones: 66
Nalidixic Acid: 523
amfonelic acid: 5
Naphthyridines: 2
Nalidixic Acid: 523
amfonelic acid: 5
Related Diseases
1.
Hypothermia
01/01/1988 - "
On the contrary, the hypothermia is partly antagonized by norepinephrine uptake inhibitors (desipramine, nomifensine, viloxazine, maprotiline, protryptiline), as well as amfonelic acid.
"
2.
Hyperalgesia
06/01/1988 - "
Amfonelic acid alone produced hyperalgesia and completely antagonized the analgesic effect of morphine.
"
3.
Duodenal Ulcer (Curling's Ulcer)
03/01/1990 - "
Reuptake blockers for norepinephrine (desmethylimipramine [17%], tomoxepine [31%], but not amfonelic acid [82%]) decreased the frequency of duodenal ulcers.
"
03/01/1990 - "
Reuptake blockers for dopamine (benztropine [73%], amfonelic acid [82%], GBR-12909 [80%]) did not protect against duodenal ulcers.
"
4.
Anorexia
01/01/1983 - "
IV injection of the dopaminergic agonists resulted in the following two basic effects: (1) d-amphetamine and amfonelic acid disrupted performance by response inhibition, which was shown not to be attributable to anorexia; (2) apomorphine and bromocriptine disrupted performance by response excitation.
"
5.
Amnesia (Dissociative Amnesia)
07/01/1987 - "
Amfonelic acid was shown to prevent the amnesic effect, to improve retrieval of the conditioned response decreased as a result of amnesia or prolonged forgetting.
"
07/01/1987 - "
Amfonelic acid exerting the central dopaminergic effect was studied on mice by the passive avoidance conditioned response method under amnesia induced by leaving the animals in a dark chamber following electrocutaneous stimulation and different terms of natural forgetting.
"
Related Drugs and Biologics
1.
Norepinephrine (Noradrenaline)
2.
Desipramine (Pertofrane)
3.
Dopamine Agonists (Dopamine Agonist)
4.
Dopamine Agents (Dopaminergic Agents)
5.
Viloxazine
6.
Nomifensine (Nomifensin)
7.
Morphine (MS Contin)
8.
Maprotiline (Ludiomil)
9.
Dopamine (Intropin)
10.
Dextroamphetamine (Dexedrine)