|1.||Anderson, George: 1 article (03/2015)|
|2.||Rodriguez, Moses: 1 article (03/2015)|
|3.||Hu, Liming: 1 article (02/2015)|
|4.||Wang, Hongxin: 1 article (02/2015)|
|5.||Ma, Chaoyang: 1 article (02/2015)|
|6.||Lv, Wenping: 1 article (02/2015)|
|7.||Tao, Guanjun: 1 article (02/2015)|
|8.||Amsellem, F: 1 article (01/2014)|
|9.||Bourgeron, T: 1 article (01/2014)|
|10.||Le Dudal, K: 1 article (01/2014)|
11/02/2001 - "The aim of this study was to determine the effect of melatonin and its precursor N-acetylserotonin on the microcirculation during acute inflammation. "
11/02/2001 - "The effect of melatonin and N-acetylserotonin herein described were observed with concentrations in the range of the nocturnal surge, providing the first evidence for a possible physiological role of these hormones in acute inflammation."
05/01/2013 - "Further research suggested the antidepressant and cognition- enhancing effects of post-serotonin metabolite, N-acetylserotonin (NAS), an agonist to tyrosine kinase B (TrkB) receptor; and link between depression and chronic inflammation-associated disorders (e.g., insulin resistance, hepatitis C virus) via inflammation-induced activation of indoleamine 2,3- dioxygenase, brain located rate-limiting enzyme of TRY - KYN metabolism. "
|4.||Body Weight (Weight, Body)
01/01/1984 - "Statistical analysis indicated that pineal N-acetylserotonin and melatonin levels per 100 gm body weight declined with age. "
07/01/1983 - "In rainbow trout forced to swim continuously at sustained speeds for six weeks, selected doses of melatonin or N-acetylserotonin (1.25 and 5.0 mg/kg body weight) injections caused no change in haematocrit. "
01/01/2001 - "By comparison, the administration of N-acetylserotonin (10 mg/kg body weight) to ANIT-injected rats did not reduce the serum levels of either hepatic enzymes or the serum total bilirubin concentration. "
01/01/2001 - "The protective effect of melatonin, 6-hydroxymelatonin and N-acetylserotonin against alpha-naphthylisothiocyanate (ANIT)-induced liver injury was investigated and compared in rats injected once with the hepatotoxicant (75 mg/kg body weight). "
02/01/1992 - "5-day morning injections to young and old rats with polypeptide pineal preparation (epithalamin) in a dose of 2.5 mg/kg of body weight induced the increase in the night peak of serotonin, N-acetylserotonin and melatonin in young and melatonin alone in old rats and did not influence 5-methoxytryptamine, 5-oxy- and 5-methoxyindoleacetic acids level. "
|5.||Melanoma (Melanoma, Malignant)
10/01/2002 - "We also documented both the in vitro transformation of serotonin to N-acetylserotonin using liquid chromatography/mass spectrometry and the generation/storage of N-acetylserotonin in cultured melanoma cells. "
01/01/1993 - "We now report that stimulation of RPMI 1846 melanoma cells with melatonergic agonists induces phosphoinositide hydrolysis in a concentration-dependent manner (EC50: N-acetylserotonin = 0.29 microM; 2-I-Melatonin = 0.39 microM; 6-Cl-Melatonin = 0.38 microM; Melatonin = 0.45 microM). "
05/01/2003 - "The effects of melatonin, N-acetylserotonin and serotonin on the growth and tyrosinase activity of SK-Mel 23 and SK-Mel 28 human melanoma cell lines were investigated. "
|4.||Serotonin (5 Hydroxytryptamine)
|5.||Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)
|8.||NG-Nitroarginine Methyl Ester (L-NAME)
|9.||NF-kappa B (NF-kB)
|10.||Biological Markers (Surrogate Marker)