|1.||Deng, Zixin: 1 article (01/2015)|
|2.||Yu, Yi: 1 article (01/2015)|
|3.||Huang, Sheng: 1 article (01/2015)|
|4.||Deng, Hai: 1 article (01/2015)|
|5.||Tong, Ming Him: 1 article (01/2015)|
|6.||Qin, Zhiwei: 1 article (01/2015)|
|7.||Mathew, Krupa Ann: 1 article (01/2014)|
|8.||Seervi, Mahendra: 1 article (01/2014)|
|9.||Pillai, Prakash Rajappan: 1 article (01/2014)|
|10.||Joseph, Jeena: 1 article (01/2014)|
01/01/2015 - "In this study, a new dithiolopyrrolone biosynthetic pathway was identified in Saccharothrix algeriensis NRRL B-24137, which was reported to produce a variety of dithiolopyrrolone natural products including thiolutin, a potential drug candidate for tumor angiogenesis inhibition. "
01/01/2015 - "Identification and characterization of the biosynthetic gene cluster of thiolutin, a tumor angiogenesis inhibitor, in Saccharothrix algeriensis NRRL B-24137."
03/01/2010 - "Thiolutin is a dithiole synthesized by Streptomyces sp. that inhibits endothelial cell adhesion and tumor growth. "
08/01/2001 - "In vivo experiments showed that thiolutin significantly suppressed angiogenesis induced by tumor cells (S-180), a pathological form of neovascularization, in a mouse dorsal air sac assay system. "
01/01/2014 - "Using this approach, we describe thiolutin, CD437 and TPEN as the most potentially valuable drug candidates for addressing drug-resistance caused by aberrant expression of Bcl-2 family proteins in tumor cells. "
03/01/2010 - "Accordingly, heat shock induction of Hsp27 limits the anti-adhesive activity of thiolutin. "
05/01/1990 - "We compared the results of this procedure with results obtained by two other procedures (approach to steady-state labeling and inhibition of transcription with Thiolutin) and also evaluated whether heat shock alter mRNA decay rates. "
12/01/1991 - "By using an episomal HSP82-lacZ fusion gene, we present evidence that lyticase and thiolutin induce heat shock gene expression at the level of transcription, whereas phenanthroline acts at a subsequent step, likely through message stabilization. "
12/01/1991 - "Third, the antibiotic thiolutin, previously demonstrated to inhibit all three yeast RNA polymerases both in vivo and in vitro, increases the RNA levels of HSP82 5- to 10-fold, those of SSA4 greater than 25-fold, and those of HSP26 greater than 50-fold under conditions in which transcription of non-heat-shock genes is blocked. "
10/01/1952 - "Tinea capitis treated with thiolutin."
|3.||DNA-Directed RNA Polymerases (RNA Polymerase)
|4.||RNA (Ribonucleic Acid)
|5.||Proteins (Proteins, Gene)
|6.||N,N,N',N'- tetrakis(2- pyridylmethyl)ethylenediamine