|1.||Cenedella, Richard J: 3 articles (06/2009 - 07/2004)|
|2.||Lizasoain, Ignacio: 1 article (01/2016)|
|3.||Dotti, Carlos G: 1 article (01/2016)|
|4.||Gabandé-Rodríguez, Enrique: 1 article (01/2016)|
|5.||Martín-Segura, Adrian: 1 article (01/2016)|
|6.||Hernández-Jiménez, Macarena: 1 article (01/2016)|
|7.||Moro, María A: 1 article (01/2016)|
|8.||Martínez-López, Diego: 1 article (01/2016)|
|9.||Ledesma, María D: 1 article (01/2016)|
|10.||Horiuchi, Motohiro: 1 article (01/2014)|
02/01/1988 - "An ultrastructural analysis of plasma membrane in the U18666A cataract."
09/01/1985 - "Most of the animals treated with U18666A every other day beginning at one-day of age developed permanent nuclear cataracts by 3-4 weeks of age. "
07/01/1983 - "Lenses from rats treated with U18666A at a level known to produce cataracts were of smaller size and accumulated total sterol at about one-half the rate of untreated controls. "
06/01/2009 - "U18666A also provided animal models for two important disorders: petite mal (absence) epilepsy and cataracts. "
02/01/1985 - "The objectives of this study were to investigate the cause of the great difference in the concentration of phospholipids between the cortex and nucleus of the ocular lens and to further investigate the mechanism of cataract induction by the sterol synthesis-inhibitor U18666A. "
10/01/2008 - "We proposed to determine how U18666a regulates APP holoprotein metabolism and trafficking in N2a mouse neuroblastoma cells stably expressing the human APP protein. "
12/01/2006 - "When NO-catalyzed degradation of HS was depressed in mouse neuroblastoma cell line (N2a) by using 3-beta[2(diethylamino) ethoxy]androst-5-en-17-one (U18666A), both ascorbate and dehydroascorbic acid restored formation of anMan-positive products that colocalized with Rab7. "
01/01/2014 - "In this study, we extensively analyzed the effects of the anti-PrP monoclonal antibody (mAb) 44B1, pentosan polysulfate (PPS), chlorpromazine (CPZ) and U18666A on the intracellular dynamics of a cellular isoform of prion protein (PrP(C)) and PrP(Sc) in prion-infected mouse neuroblastoma cells to re-evaluate the effects of those agents. "
01/01/2014 - "Comparison of the anti-prion mechanism of four different anti-prion compounds, anti-PrP monoclonal antibody 44B1, pentosan polysulfate, chlorpromazine, and U18666A, in prion-infected mouse neuroblastoma cells."
04/01/1982 - "Ubiquinone synthesis has been studied in cultured C-6 glial and neuroblastoma cells by utilizing an inhibitor, 3-beta-(2-diethylaminoethoxy) androst-5-en-17-one hydrochloride (U18666A), of cholesterol biosynthesis. "
01/01/2013 - "From this screen we identified six compounds, including U18666A, that block EBOV infection (IC(50) 1.6 to 8.0 µM) at a late stage of entry. "
01/01/2012 - "We have shown in this study that dengue virus infection was affected when the cholesterol intake in infected cells was disrupted using a cholesterol transport inhibitor, U18666A. "
09/01/2011 - "Moreover, to evaluate the anti-viral effect of U18666A in vivo, we administrated U18666A with or without pegylated interferon to chimeric mice and observed an inhibitory effect of U18666A on HCV infection and a synergistic effect with interferon. "
06/01/2009 - "U18666A subsequently became a tool for assessing the importance of molecular trafficking through the lysosomal pathway in other conditions such as atherosclerosis, Alzheimer's disease, and prion infections. "
02/15/1984 - "Treatment of the rat with U18666A [3 beta-(2-diethylaminoethoxy) androst-5-en-17-one HCl] resulted in development of a chronic seizure state and 20-40% reductions in the concentration of all major phospholipid in whole brain. "
07/14/1978 - "Starting one day after birth, weekly injection of the rat with U18666A, 3-beta(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride (10 mg/kg, s.c.), produced a reduced seizure threshold to flurothyl ether and a recurrent, spontaneous seizure state by the sixth and tenth weeks of life, respectively. "
|1.||trans- 1,4- Bis(2- chlorobenzaminomethyl)cyclohexane Dihydrochloride
|4.||Pentosan Sulfuric Polyester (Pentosan Polysulfate)