HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

2- (4'- methylpiperazino- 1- methyl)- 1,3- diazafluoranthene 1-oxide

structure

Also Known As:

AC 3579; AC-3579; NSC 170561; indeno(1,2,3-de)quinazoline, 2-((4-methyl-1-piperazinyl)methyl)-, 1-oxide

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Fluorenes: 7
        2-(4'-methylpiperazino-1-methyl)-1,3-diazafluoranthene 1-oxide: 3
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Fluorenes: 7
    - 2-(4'-methylpiperazino-1-methyl)-1,3-diazafluoranthene 1-oxide: 3

Related Diseases

1.	Leukemia P388 09/01/1973 - "Effect of AC-3579, a diazafluoranthen derivative, on murine leukemia P388 and L1210--I. "
2.	Hypertrophy 02/06/1976 - "AC-3579 (2-N-methylpiperazinomethyl-1,3-diazafluoranthen 1-oxide) produces in rat hepatocytes a hypertrophy of the endoplasmic reticulum. "
3.	Hepatocellular Carcinoma (Hepatoma) 01/01/1975 - "Effects of the diazafluoranthen derivative AC-3579 (NSC-170561), a new experimental antitumour drug, on rat hepatoma." 01/01/1975 - "After AC-3579 treatment total cholesterol was increased 3.2 fold in non-neoplastic liver and 2.5 fold in hepatoma but not in control liver." 01/01/1975 - "The effects of AC-3579 (NSC-170561), a new experimental antitumour drug which depresses phospholipid catabolism in liver, were compared in rat aflatoxin-induced hepatoma and in non-neoplastic hepatocytes surrounding the tumour. "

Related Drugs and Biologics

1.	Phospholipids (Phosphatides)
2.	Cholesterol
3.	Aflatoxins