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2- (4'- methylpiperazino- 1- methyl)- 1,3- diazafluoranthene 1-oxide
structure
Also Known As:
AC 3579; AC-3579; NSC 170561; indeno(1,2,3-de)quinazoline, 2-((4-methyl-1-piperazinyl)methyl)-, 1-oxide
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Fluorenes: 7
2-(4'-methylpiperazino-1-methyl)-1,3-diazafluoranthene 1-oxide: 3
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Fluorenes: 7
2-(4'-methylpiperazino-1-methyl)-1,3-diazafluoranthene 1-oxide: 3
Related Diseases
1.
Leukemia P388
09/01/1973 - "
Effect of AC-3579, a diazafluoranthen derivative, on murine leukemia P388 and L1210--I.
"
2.
Hypertrophy
02/06/1976 - "
AC-3579 (2-N-methylpiperazinomethyl-1,3-diazafluoranthen 1-oxide) produces in rat hepatocytes a hypertrophy of the endoplasmic reticulum.
"
3.
Hepatocellular Carcinoma (Hepatoma)
01/01/1975 - "
Effects of the diazafluoranthen derivative AC-3579 (NSC-170561), a new experimental antitumour drug, on rat hepatoma.
"
01/01/1975 - "
After AC-3579 treatment total cholesterol was increased 3.2 fold in non-neoplastic liver and 2.5 fold in hepatoma but not in control liver.
"
01/01/1975 - "
The effects of AC-3579 (NSC-170561), a new experimental antitumour drug which depresses phospholipid catabolism in liver, were compared in rat aflatoxin-induced hepatoma and in non-neoplastic hepatocytes surrounding the tumour.
"
Related Drugs and Biologics
1.
Phospholipids (Phosphatides)
2.
Cholesterol
3.
Aflatoxins