zolazepam drug combination tiletamine

07/01/1992 - "A tiletamine/zolazepam combination was used to immobilize 24 captive giant Chacoan peccaries (Catagonus wagneri) at a mean dosage rate of 2.18 mg/kg (SD = 0.46) of body weight, given intramuscularly. "
12/01/1990 - "The results suggest that the optimal Telazol dosage for the adult male koala is 7.0 mg/kg body weight. "
01/01/1997 - "Vibratory stimulation consisted of a I-mm amplitude, 75-Hz stimulation for 1 min, rest for 1 min, then continued stimulation at 1.8-mm amplitude, 90 Hz for 1 min. For EE, animals were anesthetized by administration of Telazol(3.5 mg/kg of body weight, IM) and stimulated by EE via the rectum, using a 5- to 7.5-V, 60-Hz sine wave for 1 minute of 1 sec on/ I sec off and a probe with two longitudinal electrodes and a temperature monitor. "
09/13/1996 - "Adult male rats were given a single intraperitoneal injection of Telazol dose at a of 20, 40, 80, or 120 mg/kg body weight (six rats/dose), while control rats received the vehicle only. "
04/01/1989 - "A single injection of 8 to 9 mg of Telazol per kg of body weight gave a rapid full immobilization with satisfactory analgesia, and faster recovery than other drugs for which there is no antagonist. "

01/01/2015 - "The combination tiletamine-zolazepam with detomidine proved to be effective in immobilizing captive healthy tigers but it maybe associated with hypertension and ataxia during recovery. "
07/01/2020 - "To determine the effect of intravenous vatinoxan administration on bradycardia, hypertension and level of anaesthesia induced by medetomidine-tiletamine-zolazepam in red deer (Cervus elaphus). "

10/01/2021 - "Male and female C57BL/6 mice were allocated into one of the five experimental groups, which differed in the dose of Zoletil: 0, 10, 20, 40, 80 or 100 mg/kg. A dose of 20 mg/kg was found to achieve mild sedation prior to euthanasia; mice which received this dose numerically reared and walked on the cage lid less, and showed ataxia, immobility and recumbency for longer than mice that received a lower dose. "
01/01/2015 - "The combination tiletamine-zolazepam with detomidine proved to be effective in immobilizing captive healthy tigers but it maybe associated with hypertension and ataxia during recovery. "

06/01/2021 - "Because zoletil can cause severe respiratory depression, close observation and aggressive securement of an airway is mandatory."
06/01/2021 - "We present a case of a 39-year-old man who attempted suicide by intravenously injecting a large amount of zoletil, resulting in decreased mental status and severe respiratory depression. "
06/01/2005 - "Higher mortality (36% versus 12%) occurred in group of animals treated with Domitor at 35 microg/kg and Zoletil 100 at 40 mg/kg. This difference may be linked to dose-related respiratory depression, as alterations of arterial gas levels were noted. "
01/01/1993 - "This combination produced respiratory depression comparable to tiletamine-zolazepam alone. "
01/01/1993 - "Tiletamine-zolazepam plus butorphanol produced a mild to severe respiratory depression that was dose and time dependent. "

03/01/2005 - "Tiletamine/zolazepam injection may induce transient hypoxaemia and respiratory acidosis, but acid-base status changes are clinically unimportant. "
03/01/1988 - "The arterial pH and blood gas measurements reflected the development of respiratory acidosis after administration of 23.7 mg/kg. These results support the conclusions that tiletamine-zolazepam administered intravenously is a useful and comparatively safe anesthetic agent in the cat."
11/01/1990 - "Results of this study show that (1) tiletamine-zolazepam and butorphanol tartrate produce adequate anesthesia for 25 to 50 minutes; (2) the cardiovascular and anesthetic effects of the dosing schedules were similar; and (3) tiletamine-zolazepam and butorphanol result in decreased CO and MABP with a concomitant increase in SVR, and mild respiratory acidosis."