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AF 013

O-n-octyloxime of 3-formylrifamycin SV; inhibitor of nucleic acid polymerases

Also Known As:

AF-013; rifamycin AF-013; 3-(((octyloxy)imino)methyl)rifamycin

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 4 or More Rings Heterocyclic Compounds
    - Rifamycins: 416
      - AF 013: 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Macrocyclic Lactams: 28
    - Rifamycins: 416
      - AF 013: 1

Related Diseases

1.	Neoplasms (Cancer) 06/18/1976 - "On the other hand, residual RNA synthesis in the ascites tumor cells after gamma-irradiation was inhibited by rifampicin AF/013. " 06/18/1976 - "The residual RNA synthesis in Yoshida ascites tumor cells following exposure to ultraviolet radiation was insensitive to rifampicin AF/013, an inhibitor of initiation of RNA synthesis in eukaryotic cells. "
2.	Ascites 06/18/1976 - "On the other hand, residual RNA synthesis in the ascites tumor cells after gamma-irradiation was inhibited by rifampicin AF/013. " 06/18/1976 - "The residual RNA synthesis in Yoshida ascites tumor cells following exposure to ultraviolet radiation was insensitive to rifampicin AF/013, an inhibitor of initiation of RNA synthesis in eukaryotic cells. " 06/18/1976 - "In vitro synthesis of RNA on ultraviolet-irradiated ascites chromatin likewise was resistant to rifampicin AF/013. "

Related Drugs and Biologics

1.	RNA (Ribonucleic Acid)
2.	Rifampin (Rifampicin)
3.	Chromatin