IA 3 (IA-3)

RN given refers to parent cpd

Also Known As:

IA-3; 6-chloroindazolelucanthone; IA 3, monomethanesulfonate; 8-chloro-N,N-diethyl-5-methyl-2H-(1)benzothiopyrano(4,3,2-cd)indazole-2-ethanamine, monomethanesulfonate

Networked: 21 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thioxanthenes: 11
    - Lucanthone: 76
      - IA 3: 21
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Xanthenes: 65
      - Xanthones: 211
        Lucanthone: 76
        IA 3: 21
      - Thioxanthenes: 11
        Lucanthone: 76
        IA 3: 21

Experts

1.	Baggerman, Jessica O: 1 article (07/2020)
2.	Hergenreder, Jerilyn E: 1 article (07/2020)
3.	Johnson, Bradley J: 1 article (07/2020)
4.	Kim, Jongkyoo: 1 article (07/2020)
5.	Rounds, Whitney: 1 article (07/2020)
6.	Smith, Zachary K: 1 article (07/2020)
7.	Thompson, Alex J: 1 article (07/2020)
8.	Greving, Jacoba P: 1 article (01/2019)
9.	Mensing, Liselore A: 1 article (01/2019)
10.	Rinkel, Gabriel J E: 1 article (01/2019)

Related Diseases

1.	Epilepsy (Aura) 04/12/2019 - "One-year follow-up was available in all patients, and showed 11 Engel class IA, 4 class IB, 4 class II, and 3 class III/IV. Two-year follow-up was available in 19 patients, and showed 9 class IA, 3 class IB, 1 class ID, 3 class II, and 3 class III/IV. This study highlights the individual and combined values of multiple noninvasive modalities for the evaluation of nonlesional operculoinsular epilepsy. "
2.	Pelvic Inflammatory Disease (Pelvic Inflammatory Diseases) 02/01/1999 - "This study examined the response to acidic conditions of four gonococcal isolates -NRL38874 (Proto/IB-2), NRL38884 (Pro/IA-2), NRL38953 (Proto/IB-3) and NRL39029 (Pro/IA-3) - obtained from various sites in patients in whom a diagnosis of pelvic inflammatory disease had been made by laparoscopic examination. "
3.	Rupture 08/30/2022 - "Multivariate analysis demonstrated that: (1) IA location is the strongest factor associated with IA rupture status at diagnosis; (2) Risk factor awareness (hypertension, smoking) increases the likelihood of being diagnosed with unruptured IA; (3) Patients with ruptured IAs in high-risk locations tend to be older, and their IAs are smaller; (4) Smokers with ruptured IAs tend to be younger, and their IAs are larger; (5) Female patients with ruptured IAs tend to be older, and their IAs are smaller; (6) IA size and age at rupture correlate. " 01/01/2019 - "Despite familial aneurysms being smaller and more often located at low risk sites than sporadic IA, 3 familial patients had aneurysmal subarachnoid hemorrhage (0.77 ruptures per 100 aneurysm-years [95% CI, 0.20-2.09]) compared with 7 sporadic patients (0.51 ruptures per 100 aneurysm-years [95% CI, 0.22-1.01]). "
4.	Neoplasms (Cancer) 01/01/2002 - "The tumors were staged as follows: stage IA, 3 cases; stage IB, 13 cases; stage II, 3 cases; stage III, 2 cases. " 10/01/2003 - "Twenty-five patients (median age, 29 years) with borderline ovarian tumors, including 10 with stage IA, 3 with stage IC, 1 with stage IIIA and 11 with unstaged disease, underwent fertility-sparing surgery, consisting of unilateral adnexectomy in 19, unilateral adnexectomy with contralateral cystectomy in 5 and unilateral cystectomy in 1. No disease recurred, providing an overall survival of 100%. "
5.	Carcinoma (Carcinomatosis) 01/01/2001 - "The mean age of patients were 36 years and the clinical staging of FIGO found : 3 stages Ia, 3 Ib, 7 IIa, 14 IIb, 7 IIIa, 7 IIIb, 4 IVa, 5 IVb The diagnosis of carcinoma was in 6 cases(12%) at first trimester, in 6 cases(12%) at midtrimester, in 13 cases(27%) at third trimester, in 19 cases(28%) after delivery. " 05/01/2012 - "There were 9 (6.5%) cases in group 1, 30 (21.7%) cases in group 2, 29 (21.0%) cases in group 3 and 70 (50.7%) cases in group 4. There were 5 (5/9) cases with stage Ia, 3 (3/9) cases with stage Ib and 1 (1/9) case with stage II or above in group 1; 11 (36.7%, 11/30) cases with stage Ia, 15 (50.0%, 15/30) cases with stage Ib and 4 (13.3%, 4/30) cases with stage II or above in group 2; 5 (17.2%, 5/29) cases with stage Ia, 14 (48.3%, 14/29) cases with stage Ib was and 10 (34.5%, 10/29) cases with stage II or above in group 3; 7 (10.0%, 7/70) cases stage with Ia, 35 (50.0%, 35/70) cases with stage Ib and 28 (40.0%, 28/70) cases with stage II or above in group 4. The results showed that there was an increasing trend of advanced cervical carcinoma at diagnosis for the patients with longer last cervical cancer screening time (P < 0.05). "

Related Drugs and Biologics

1.	IA 4
2.	Sodium Glutamate (Accent)
3.	Insulin (Novolin)
4.	Doxorubicin (Adriamycin)
5.	Cisplatin (Platino)
6.	Chromium
7.	Angiotensin II
8.	gadoteridol (Prohance)

Related Therapies and Procedures

1.	Blalock-Taussig Procedure
2.	Cystectomy