|1.||Bernstein, Paul S: 15 articles (10/2014 - 10/2002)|
|2.||Johnson, Elizabeth J: 14 articles (09/2014 - 03/2002)|
|3.||Chew, Emily Y: 12 articles (07/2015 - 09/2007)|
|4.||Ma, Le: 9 articles (01/2015 - 01/2010)|
|5.||Gellermann, Werner: 9 articles (06/2013 - 10/2002)|
|6.||Lin, Xiao-Ming: 8 articles (03/2015 - 01/2010)|
|7.||Willett, Walter C: 7 articles (12/2015 - 01/2005)|
|8.||Zou, Zhi-Yong: 7 articles (03/2015 - 02/2012)|
|9.||Xu, Xian-Rong: 7 articles (03/2015 - 02/2012)|
|10.||Huang, Yang-Mu: 7 articles (03/2015 - 02/2012)|
|1.||Macular Degeneration (Age-Related Maculopathy)
11/01/2011 - "Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration: the Zeaxanthin and Visual Function Study (ZVF) FDA IND #78, 973."
10/01/2014 - "The available evidence suggests a beneficial effect of zeaxanthin against the progression of age-related macular degeneration (AMD). "
01/01/2014 - "Zeaxanthin (Zea) is a major carotenoid pigment contained in human retina, and its daily supplementation associated with lower risk of age-related macular degeneration. "
07/31/2013 - "The carotenoid-derived volatile, β-ionone, was identified in both standard yellow sweet corn ('Hybrix5') and a zeaxanthin-enhanced experimental variety ('HZ') designed for sufferers of macular degeneration. "
03/01/2008 - "Increasing zeaxanthin in common foods such as potatoes by traditional plant breeding or by genetic engineering could contribute to an increased intake of this carotenoid and, consequently, to a decreased risk of age-related macular degeneration. "
01/01/2014 - "A stronger association between nuclear cataract and blood zeaxanthin might be noted for the studies conducted in the European Nations. "
06/01/2006 - "After multivariate adjustment, the highest quintile of plasma zeaxanthin was significantly associated with reduced risk of ARM (OR=0.07; 95% CI: 0.01-0.58; P for trend=0.005), nuclear cataract (OR=0.23; 95% CI: 0.08-0.68; P for trend=0.003) and any cataract (OR=0.53; 95% CI: 0.31-0.89; P for trend=0.01). "
03/01/2006 - "I recently read that zeaxanthin may help prevent cataracts. "
08/01/2012 - "Zeaxanthin is a predominant xanthophyll in human eyes and may reduce the risk of cataracts and age-related macular degeneration. "
06/01/2006 - "These results are strongly suggestive of a protective role of the xanthophylls, in particular zeaxanthin, for the protection against ARM and cataract."
|3.||Eye Diseases (Eye Disease)
11/01/2005 - "The dietary carotenoid zeaxanthin protects against age-related eye disease by preventing apoptosis in photoreceptor cells. "
11/01/2011 - "The purpose of this study is to evaluate whether dietary supplementation with the carotenoid zeaxanthin (Zx) raises macula pigment optical density (MPOD) and has unique visual benefits for patients with early atrophic macular degeneration having visual symptoms but lower-risk National Institute of Health/National Eye Institute/Age-Related Eye Disease Study characteristics. "
09/01/2014 - "In addition, lutein and zeaxanthin may be protective against eye disease because they absorb damaging blue light that enters the eye. "
11/01/2012 - "The primary purpose of the Age-Related Eye Disease Study 2 (AREDS2) is to evaluate the efficacy and safety of lutein plus zeaxanthin (L+Z) and/or ω-3 long-chain polyunsaturated fatty acid (LCPUFA) supplementation in reducing the risk of developing advanced AMD. "
02/01/2011 - "Modalities reviewed include (1) nutritional supplements such as the Age-Related Eye Disease Study (AREDS) formula, lutein and zeaxanthin, omega-3 fatty acid, and berry extracts, (2) lifestyle modifications, including smoking and body-mass-index, and (3) filtering sunlight, i.e. "
01/01/2015 - "Tumor-bearing eye mass and tumor mass in the control group were significantly greater than those in zeaxanthin treated group. "
01/01/2015 - "Quantitative image analysis revealed that the tumor size was reduced by 56% in eyes treated with low dosages of zeaxanthin and 92% in eyes treatment with high dosages of zeaxanthin, as compared to the controls. "
01/01/2007 - "The results of the photocarcinogenesis experiment were increased tumor-free survival time, reduced tumor multiplicity and total tumor volume in lutein/zeaxanthin-treated mice in comparison with control irradiated animals fed the standard diet. "
01/01/2007 - "Results showed that the anti-tumor activities of the di-acetylation of lutein and di-acetylation of zeaxanthin decreased significantly (p<0.05) at 50 micromol/L. "
01/01/2007 - "The anti-proliferative effects of di-acetylated lutein or zeaxanthin on the human mouth epithelial cancer line KB cell were compared with controls of their original counterparts. "
|5.||Lung Neoplasms (Lung Cancer)
05/15/2013 - "However, because of potential increased incidence of lung cancer in former smokers, lutein + zeaxanthin could be an appropriate carotenoid substitute in the AREDS formulation. "
01/01/2014 - "The AREDS-2 study has shown that lutein and zeaxanthin may substitute beta-carotene because of its potential relationship with increased lung cancer incidence. "
12/01/2013 - "Because beta-carotene is associated with increased lung cancer in former smokers, lutein/zeaxanthin could replace beta-carotene and provide an incremental increase in the beneficial effects beyond the effects of the AREDS formulation. "
06/01/2005 - "For women, serum levels of alpha-carotene and zeaxanthin/lutein were inversely associated with risk of lung cancer, but the association was not significant. "
02/01/2014 - "The Age-Related Eye Disease Study 2 (AREDS2) assessed the value of substituting lutein/zeaxanthin in the AREDS formulation because of the demonstrated risk for lung cancer from beta carotene in smokers and former smokers and because lutein and zeaxanthin are important components in the retina. "
|7.||Ascorbic Acid (Vitamin C)
|10.||beta Carotene (Betacarotene)
|3.||Drug Therapy (Chemotherapy)