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trichlorofluoromethane (Freon 11)
refrigerant, aerosol propellant; RN given refers to parent cpd; structure
Also Known As:
Freon 11
;
trichloromonofluoromethane
;
fluorotrichloromethane
; FC-11; Genetron 11; trichlorofluoromethane hydrate; trichlorofluoromethane, (18)F-labeled
Networked:
6
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Halogenated Hydrocarbons: 42
Chlorinated Hydrocarbons: 240
Chlorofluorocarbons: 70
Methane Chlorofluorocarbons: 2
trichlorofluoromethane: 6
Fluorinated Hydrocarbons: 4
Chlorofluorocarbons: 70
Methane Chlorofluorocarbons: 2
trichlorofluoromethane: 6
Related Diseases
1.
Cardiac Arrhythmias (Arrythmia)
01/01/1975 - "
Trichlorofluoromethane (FC 11) provoked arrhythmia in all three animal species, dichlorodifluoromethane (FC 12) in monkeys and rats but not in mice, and difluoroethane (FC 152a) only in rats.
"
06/01/1980 - "
The purpose of this investigation was to determine whether inhalation of a freon gas mixture, the propellant of the commercial metered-dose aerosols, consisting of freon 11, freon 12, and freon 114, reduces the bronchodilating effects of inhaled salbutamol or ipratropium bromide or causes cardiac arrhythmias in control, asthmatic and bronchitic subjects.
"
2.
Poisoning
05/01/1994 - "
A case of lethal poisoning due to trichlorofluoromethane (FC11) inhalation is described.
"
05/01/1994 - "
A fatal case of trichlorofluoromethane (Freon 11) poisoning.
"
3.
Neoplasms (Cancer)
01/01/1978 - "
The results of the bioassay of trichlorofluoromethane in Osborne-Mendel rats for possible carcinogenicity are not conclusive because inadequate numbers of rats survived sufficiently long enough to be at risk from late-developing tumors.
"
01/01/1978 - "
No groups of male or female mice dosed with trichlorofluoromethane had significantly increased tumor incidences relative to their respective control groups.
"
01/01/1978 - "
Results of a time-adjusted statistical analysis of tumor incidence in rats indicated no significant positive associations between administration of trichlorofluoromethane and tumor incidence.
"
4.
Necrosis
05/01/1980 - "
The freezing action of Freon 11 is postulated as the cause of tissue necrosis.
"
05/01/1980 - "
Accidental ingestion of trichlorofluoromethane (Freon 11) by a healthy adult male resulted in necrosis and multiple perforations of the stomach.
"
5.
Cardiomyopathies (Cardiomyopathy)
04/01/1975 - "
Cardiomyopathy predisposes hamsters to trichlorofluoromethane toxicity.
"
Related Drugs and Biologics
1.
trichlorofluoromethane (Freon 11)
2.
dichlorodifluoromethane (FC 12)
3.
Chlorofluorocarbons (Freon)
4.
Ipratropium (Ipratropium Bromide)
5.
Albuterol (Salbutamol)
6.
Aerosols
7.
Freon 114