|1.||Supuran, Claudiu T: 9 articles (09/2014 - 12/2003)|
|2.||Potter, Barry V L: 8 articles (10/2015 - 02/2005)|
|3.||Purohit, Atul: 6 articles (02/2014 - 02/2005)|
|4.||Scozzafava, Andrea: 6 articles (01/2014 - 12/2003)|
|5.||Winum, Jean-Yves: 5 articles (09/2015 - 12/2003)|
|6.||Vullo, Daniela: 5 articles (09/2014 - 12/2003)|
|7.||Leese, Mathew P: 5 articles (02/2014 - 02/2005)|
|8.||Reed, Michael J: 5 articles (10/2008 - 02/2005)|
|9.||Newman, Simon P: 3 articles (02/2014 - 02/2005)|
|10.||Ferrandis, Eric: 3 articles (02/2014 - 09/2007)|
|1.||Breast Neoplasms (Breast Cancer)
09/22/2015 - "The efficacy of 5 novel ureido-substituted sulfamate CAIX inhibitors were assessed in increasingly complex breast cancer models, including cell lines in normoxia and hypoxia, 3D spheroids and an ex-vivo explant model utilizing fresh biopsy tissue from different breast cancer subtypes. "
03/01/2005 - "An impressing number of inhibitors of STSs of the sulfamate type have been reported in the last years, with several compounds, such as 667COUMATE among others, progressing to clinical trials for the treatment of hormone-dependent tumors (breast and prostate cancers). "
03/01/2006 - "STX64 (667 Coumate), a tricylic coumarin-based sulfamate that irreversibly inhibits STS activity, was selected for entry into the first phase I trial of a STS inhibitor in postmenopausal women with breast cancer. "
11/01/2009 - "New carbon-11-labeled sulfamate derivatives were first designed and synthesized as potential PET dual aromatase-steroid sulfatase inhibitor (DASSI) radiotracers for imaging of aromatase and STS expression in breast cancer. "
10/01/2008 - "Recently, 667 COUMATE, an irreversible type of inhibitor which utilizes a phenol sulfamate ester as its active pharmacophore, has completed a Phase I clinical trial in postmenopausal women with breast cancer. "
|2.||Weight Loss (Weight Reduction)
11/01/2007 - "In contrast, topiramate (a sulfamate moiety) appears to inhibit specific (CA) enzymes II and V. Four placebo-controlled trials with topiramate have demonstrated positive results in weight loss. "
01/01/2013 - "Topiramate is a sulfamate-substituted monosaccharide anticonvulsant that is associated with anorexia and weight loss and has been used to treat binge eating disorder and bulimia nervosa. "
10/08/2015 - "Subsequent drug discovery projects were initiated to develop the core aryl O-sulfamate pharmacophore that, over some 20 years, have led to steroidal and nonsteroidal drugs in numerous preclinical and clinical trials, with promising results in oncology and women's health, including endometriosis. "
|4.||Bipolar Disorder (Mania)
|5.||Migraine Disorders (Migraine)
05/01/2010 - "Topiramate, a sulfamate-substituted monosaccharide classically used as an antiepileptic medication, has been widely used since its recent indication for migraine prophylaxis. "
03/01/2012 - "Topiramate is a sulfamate-substituted monosaccharide mainly used to treat epilepsy in children and adults and prophylaxis of migraine. "
12/01/2011 - "Topiramate is a sulfamate-substituted monosaccharide marketed since 1996, and approved by the FDA for seizure disorders at doses up to 400 mg/day and for the prevention of migraine headaches at doses up to 100 mg/day. "
01/01/2010 - "Topiramate is a sulfamate-substituted monosaccharide used in the treatment of seizures, and prophylaxis of migraine. "
01/01/2009 - "Topiramate is a sulfamate-substituted monosaccharide mainly used to treat epilepsy in children and adults and for prophylaxis of migraine. "
|9.||Carbonic Anhydrases (Carbonic Anhydrase)
|10.||Steryl-Sulfatase (Steroid Sulfatase)
|1.||Heterologous Transplantation (Xenotransplantation)