|1.||Choi, Yung Hyun: 7 articles (07/2013 - 09/2007)|
|2.||Ahmad, Nihal: 5 articles (04/2015 - 08/2003)|
|3.||Han, Min Ho: 5 articles (07/2013 - 09/2007)|
|4.||Kim, Gi-Young: 5 articles (07/2013 - 01/2008)|
|5.||Das, Mukul: 5 articles (01/2013 - 12/2004)|
|6.||Ansari, Kausar M: 5 articles (01/2013 - 12/2004)|
|7.||Lee, Won Ho: 4 articles (11/2009 - 09/2007)|
|8.||Ulrichová, Jitka: 4 articles (06/2009 - 01/2004)|
|9.||Ulrichová, J: 4 articles (05/2007 - 01/2003)|
|10.||Li, Weifeng: 3 articles (10/2014 - 08/2012)|
11/01/1985 - "The results demonstrated that the Sanguinarine-containing mouthrinse was effective in reducing plaque formation and retarding the development of gingivitis."
04/01/1990 - "[Evaluation of the efficacy of sanguinarine using the experimental gingivitis model]."
08/01/1990 - "A critical comparison of the numerous clinical studies on sanguinarine indicates an extreme divergence of reported effects on plaque/gingivitis, ranging from significant reductions to findings of no detectable effect. "
11/01/1988 - "The findings of this study would suggest that the Veadent mouthrinse would at most only have a limited rôle as an inhibitor of plaque and gingivitis."
06/01/1996 - "The in vitro cytotoxicity of sanguinarine chloride, a dental product used in the treatment of gingivitis and plaque, was compared using cell lines and primary cells from oral human tissues. "
|2.||Prostatic Neoplasms (Prostate Cancer)
04/01/2006 - "The aim of this study was to investigate whether expression of Cox-2 is effective against prostate cancer cell apoptosis triggered by sanguinarine, the quaternary benzophenanthridine alkaloid with antineoplastic properties. "
01/01/2012 - "In this study, we identified sanguinarine as a potent inhibitor of Stat3 activation which was able to suppress prostate cancer growth, migration, and invasion. "
01/01/2012 - "These data demonstrate that sanguinarine is a potent Stat3 inhibitor and it could be developed as a therapeutic agent for prostate cancer with constitutive activation of Stat3."
01/01/2012 - "Sanguinarine inhibits constitutive as well as IL6-induced phosphorylation of Stat3 at both Tyr705 and Ser727 in prostate cancer cells. "
01/01/2012 - "Sanguinarine, a benzophenanthridine alkaloid derived primarily from the bloodroot plant, was identified previously as a novel inhibitor of survivin that selectively kills prostate cancer cells over "normal" prostate epithelial cells. "
|3.||Melanoma (Melanoma, Malignant)
05/01/2015 - "At 2 hours, sang-np killed a portion of melanoma cells, increasing to percentages comparable to free sanguinarine by 24 hours. "
05/01/2015 - "To exploit sanguinarine's observed activity against melanoma, a targeted delivery system is required. "
05/01/2015 - "However, when used in a controlled fashion, sanguinarine imparts selective cytotoxic/anti-proliferative activity through multiple mechanisms against human/ murine melanoma. "
05/01/2015 - "Characterization and assessment of nanoencapsulated sanguinarine chloride as a potential treatment for melanoma."
04/05/2013 - "Taking together, our data indicate that sanguinarine is a very rapid inducer of human melanoma caspase-dependent cell death that is mediated by oxidative stress."
|4.||Skin Neoplasms (Skin Cancer)
07/01/2007 - "Based on this data, we suggest that sanguinarine could be developed as an agent for the management of conditions elicited by UV exposure including skin cancer. "
07/01/2007 - "Protective effect of sanguinarine on ultraviolet B-mediated damages in SKH-1 hairless mouse skin: implications for prevention of skin cancer."
08/01/2003 - "We suggest that sanguinarine could be developed as a drug for the management of hyperproliferative skin disorders, including skin cancer."
12/01/2009 - "Data from the present study support the concept that sanguinarine can be effective in melanoma skin cancer."
|3.||chlorhexidine gluconate (Dyna-Hex)
|8.||DNA (Deoxyribonucleic Acid)
|10.||2,3- bis(2- hydroxyethylsulfanyl)- (1,4)naphthoquinone
|2.||Heterologous Transplantation (Xenotransplantation)
|3.||Traditional Medicine (Folk Remedies)