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E 10 (E-10)

prolongs duration of action potential
Also Known As:
E-10; N-(2-aminoethyl)-N-(2-(octylamino)ethyl)glycine monohydrochloride, mixt. with N,N-bis(2-(octylamino)ethyl)glycine monohydrochloride
Networked: 113 relevant articles (2 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Rodríguez, Rosalía: 3 articles (02/2006 - 08/2005)
2. Barral, Patricia: 3 articles (02/2006 - 08/2005)
3. Villalba, Mayte: 3 articles (02/2006 - 08/2005)
4. Batanero, Eva: 3 articles (02/2006 - 08/2005)
5. Villalba, M: 2 articles (01/2007 - 03/2005)
6. Florido, J F: 2 articles (01/2007 - 03/2005)
7. Rodríguez, R: 2 articles (01/2007 - 03/2005)
8. Quiralte, J: 2 articles (01/2007 - 03/2005)
9. Lahoz, C: 2 articles (01/2007 - 03/2005)
10. Arias de Saavedra, J M: 2 articles (01/2007 - 03/2005)

Related Diseases

1. Neoplasm Metastasis (Metastasis)
2. Hypertrophy
3. Hypertension (High Blood Pressure)
02/01/2001 - "Compared to the normotensive subjects, the five OHyp who developed hypertension had more pronounced alterations of LV diastolic function, that is, significantly higher mitral A (54 +/- 7 v 44 +/- 9 cm/sec, hypertensives v normotensives, P < .05), lower E/A ratio (1.31 +/- 0.14 v 1.82 +/- 0.48, P < .05), increased systolic-to-diastolic pulmonary vein flow ratio (1.11 +/- 0.3 v 0.81 +/- 0.16, P < .005), longer myocardial isovolumic relaxation time (57 +/- 7 v 46 +/- 12 msec, P < .05) as well as smaller myocardial E (10 +/- 1 v 13 +/- 2 cm/sec, P < .05) and E/A ratio (1.29 +/- 0.25 v 1.78 +/- 0.43, P < .05), despite similar LV mass (91 +/- 16 v 93 +/- 18 g/m2). "
05/15/2006 - "During transient hypertension, irrespective of forepaw stimulation, BP increases (i.e., >10 mm Hg) produced a transient increase in the blood oxygen level-dependent (BOLD) intensity resulting in a significant numbers of voxels correlating to the BP time courses (P < 0.05), and the number of these voxels increased as BP increased, becoming substantial at BP > 30 mm Hg. The activation patterns with BP increases and stimulation overlapped spatially resulting in an enhanced cerebral activation to simultaneous forepaw stimulation (P < 0.05). "
03/01/1982 - "The effects of the converting enzyme inhibitor, SQ 14,225, on the renin-angiotensin system, adrenal function and blood pressure were investigated in 14 hypertensive patients, i.e., 10 with essential hypertension (EH) and 4 with renovascular hypertension (RVH). "
03/01/2004 - "This was a multicenter, prospective, randomized, double-blind, parallel group study, to evaluate the efficacy and tolerability of manidipine (M; 10-20 mg/day), in comparison with enalapril (E; 10-20 mg/day) in the treatment of hypertension in 136 patients with CKD secondary to primary renoparenchymal disease. "
4. Breast Neoplasms (Breast Cancer)
5. Myocardial Infarction

Related Drugs and Biologics

1. Tocotrienols
2. Tocopherols
3. alpha-Tocopherol
4. Atrial Natriuretic Factor (ANF)
5. Enalapril
6. delta-tocopherol
7. manidipine
8. Lactic Acid
9. Interleukin-8 (Interleukin 8)
10. Oxygen

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Transplantation (Transplant Recipients)
3. Radiotherapy
4. Preoperative Care
5. Cholecystectomy